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Table 3 Illness severity data for patients split by ventricular volume change (average values and standard deviations; N = 113)

From: Longitudinal assessment of ventricular volume trajectories in early-stage schizophrenia: evidence of both enlargement and shrinkage

 

Normal

VS

VE

p-value

Adjusted p-value

Age of first symptoms

27.77 (6.83)

23.90 (6.50)

27.72 (7.45)

0.0726

0.7109

Duration of untreated psychosis (months)*

7.03 (14.08)

3.05 (7.53)

6.74 (7.58)

0.1220

0.7320

Chlorpromazine equivalent V1*

379.37 (244.50)

376.21 (196.06)

344.40 (131.19)

0.8331

1.0000

Chlorpromazine equivalent V2*

264.82 (191.41)

311.57 (161.71)

315.80 (212.86)

0.3744

1.0000

PANSS - P V1*

12.19 (3.99)

12.74 (3.51)

14.65 (4.72)

0.0821

0.7109

PANSS - N V1

17.06 (4.93)

19.79 (7.76)

17.55 (5.38)

0.5453

1.0000

PANSS - G V1

30.26 (7.58)

35.79 (8.43)

34.00 (7.30)

0.0161

0.2099

PANSS total V1*

59.51 (13.82)

68.32 (17.31)

66.20 (14.66)

0.0711

0.7109

PANSS - P V2*

9.89 (3.57)

9.37 (3.18)

11.76 (4.93)

0.1297

0.7320

PANSS - N V2*

14.55 (5.42)

13.89 (5.65)

17.95 (5.31)

0.0327

0.3903

PANSS - G V2*

25.73 (6.94)

25.26 (6.44)

31.90 (8.79)

0.0127

0.1773

PANSS total V2*

59.51 (13.82)

68.32 (17.31)

66.20 (14.66)

0.0711

0.7109

GAF V1

65.27 (15.24)

58.22 (16.96)

60.38 (18.59)

0.2282

0.9126

GAF V2*

75.36 (14.93)

75.84 (12.53)

66.86 (14.17)

0.0325

0.3903

  1. Note: *=Shapiro-Wilk test indicated violation of assumption of normality; PANSS - Positive and Negative Syndrome Scale (N - Negative symptoms; P - Positive symptoms; G - General psychopathology); GAF - Global Assessment of Functioning scale