measure | CESD | PHQ2 | LS5 | LS6C | LS7C | MCS | PSS |
|---|
CESD |  | 5.954 (< 0.001) | 4.099 (0.148) | 0.804 (0.597) | 0.303 (0.747) | -0.469 (0.001) | 0.751 (< 0.001) |
PHQ2 | 0.081 (< 0.001) |  | 0.079 (0.808) | 0.007 (0.968) | 0.018 (0.870) | -0.078 (< 0.001) | 0.092 (< 0.001) |
LS5 | 0.007 (0.148) | 0.011 (0.808) |  | 0.448 (< 0.001) | 0.211 (< 0.001) | -0.001 (0.860) | -0.001 (0.906) |
LS6C | 0.005 (0.597) | 0.003 (0.968) | 1.508 (< 0.001) |  | 0.505 (< 0.001) | 0.003 (0.802) | -0.015 (0.272) |
LS7C | 0.006 (0.747) | 0.026 (0.870) | 2.250 (< 0.001) | 1.611 (< 0.001) |  | 0.012 (0.600) | -0.027 (0.297) |
MCS | -0.297 (0.001) | -3.597 (< 0.001) | -0.388 (0.860) | 0.302 (0.802) | 0.391 (0.600) |  | -0.347 (0.009) |
PSS | 0.380 (< 0.001) | 3.393 (< 0.001) | -0.232 (0.906) | -1.174 (0.272) | -0.688 (0.297) | -0.276 (0.009) |  |
- The above numbers were calculated by fitting a mixed effect model for each outcome variable. The column names are the independent variables and the row names are the dependent variables. The mixed effect models had a random slope for time for each participant. These random slopes were extracted and saved. Then, linear models were run comparing the generated slopes for the independent variables to the slopes from the dependent variable. The numbers above are estimates from the linear models. The numbers in parentheses are p-values rounded to three decimal places
- CESD: Center for Epidemiological Studies Depression Scale [46, 71]. PHQ2: Patient Health Questionnaire 2-question depression screener. LS5: Life Simple 7 score that does not include diet and physical activity (0–10). LS6C: Life Simple 7 score that does not include diet (0–12). The C denotes physical activity was calculated based on the CMS physical activity score or weekly reported physical activity minutes if CMS physical activity was missing. LS7C: Life Simple 7 score (0–14). The C denotes physical activity was calculated based on the CMS physical activity score or weekly reported physical activity minutes if CMS physical activity was missing. MCS: Mental component score of the SF-36. PSS: Perceived Stress Scale score
- Some of the mixed effects models were singular when generating the slopes. Even so, the results are as expected (LS7 variables correlate with LS7 variables, and mental health variables correlate with mental health variables). We performed a different analysis to answer the same question to verify the results from the above analysis (see below)
- Interpretation example: A 1-unit change in CES-D slope is associated with a 0.079 unit change in PHQ-2 slope (p < 0.001), where the slopes are the linear change in score over all time points.
- Overall interpretation: There is no association of change in mental health measures with change in cardiovascular health scores. The change in one mental health measure was associated with the change in other mental health measures.
- Significant findings are bolded.
