Table 2 Univariable and multivariable logistic regression analysis of the risk factors associated with depressive symptoms

univariable logistic regression

 Family structure

  Living in a two-parent family

1.00 (reference)

1.00 (reference)

1.00 (reference)

  Living in a single-parent family

2.96 (1.36–6.43)

0.006

2.06 (0.53–7.98)

0.295

3.14 (1.16–8.49)

0.025

  Living with others

3.05 (1.11–8.41)

0.031

5.15 (1.14–23.32)

0.033

1.96 (0.49–7.77)

0.339

 Family relationship

  Good

1.00 (reference)

1.00 (reference)

1.00 (reference)

  Average/Poor^&

5.00 (2.55–9.84)

< 0.001

7.58 (2.52–22.83)

< 0.001

3.54 (1.50–8.38)

0.004

 HSS

  Above average

1.00 (reference)

1.00 (reference)

1.00 (reference)

  Average/Poor^&

1.75 (1.03–2.99)

0.040

2.85 (1.17–6.97)

0.022

1.46 (0.72–2.98)

0.293

 Academic performance

  Good

1.00 (reference)

1.00 (reference)

1.00 (reference)

  Average

2.20 (1.13–4.25)

0.020

3.27 (1.18–9.03)

0.022

1.61 (0.67–3.88)

0.291

  Poor

3.52 (1.80–6.88)

< 0.001

2.86 (0.99–8.29)

0.052

4.10 (1.64–10.27)

0.003

 Current alcohol consumption

  No

1.00 (reference)

1.00 (reference)

1.00 (reference)

  Yes

3.05 (1.74–5.36)

< 0.001

3.09 (1.26–7.57)

0.014

2.74 (1.31–5.74)

0.007

  FKBP5-12 CpG 1 (per 1% increase)

0.79 (0.62-1.00)

0.053

0.72 (0.47–1.11)

0.137

0.84 (0.62–1.12)

0.230

  FKBP5-47 CpG 36 (per 1% increase)

0.95 (0.91-1.00)

0.049

0.96 (0.89–1.03)

0.284

0.96 (0.89–1.02)

0.187

multivariable logistic regression

aOR (95% CI)^#

P

aOR (95% CI)^#

P

aOR (95% CI)^#

P

FKBP5-12 CpG 1 (per 1% increase)

0.77 (0.58–1.01)

0.055

0.64 (0.37–1.09)

0.100

0.79 (0.57–1.10)

0.169

FKBP5-47 CpG 36 (per 1% increase)

0.95 (0.89-1.00)

0.063

0.93 (0.84–1.02)

0.119

0.97 (0.90–1.05)

0.468