| Treatment Group | |||||
---|---|---|---|---|---|---|
memantine+sertraline (n = 35) | placebo+sertraline (n = 30) | P value | ||||
Mean±SD | Count (%) | Mean±SD | Count (%) | |||
Age (years) | 35.03±11.35 |  | 334.83±10.30 |  |  | |
Gender | Female | Â | 27 (77.1%) | Â | 17 (56.7%) | 0.07 |
Male | Â | 8 (22.9%) | Â | 13 (43.3%) | ||
Education | Illiterate | Â | 0 (0.0%) | Â | 1 (3.3%) | 0.30 |
Primary | Â | 1 (2.9%) | Â | 2 (6.7%) | ||
Secondary | Â | 9 (25.7%) | Â | 5 (16.7%) | ||
High school diploma | Â | 9 (25.7%) | Â | 13 (43.3%) | ||
University Education | Â | 16 (45.7%) | Â | 9 (30.0%) | ||
Marital status | Single | Â | 18 (51.4%) | Â | 11 (36.7%) | 0.08 |
Married | Â | 14 (40.0%) | Â | 17 (56.7%) | ||
Divorced | Â | 0 (0.0%) | Â | 2 (6.7%) | ||
Separated | Â | 3 (8.6%) | Â | 0 (0.0%) | ||
Employment | Employed | Â | 18 (51.4%) | Â | 18 (60.0%) | 0.71 |
Unemployed | Â | 7 (20.0%) | Â | 4 (13.3%) | ||
Housewife | Â | 10 (28.6%) | Â | 8 (26.7%) | ||
Previous treatment | Yes | Â | 4 (11.4%) | Â | 2 (6.7%) | 0.50 |
No | Â | 31 (88.6%) | Â | 28 (93.3%) | ||
Y-BOCS score (week 0) | Total | 27.88±5.65 |  | 30.11±5.79 |  | 0.12 |
Obsession | 15.07±2.57 |  | 15.53±2.50 |  | 0.46 | |
Compulsion | 12.70±4.30 |  | 14.57±3.81 |  | 0.07 | |
WCST score (week 0) | Error | 22.89±9.85 |  | 22.09±10.63 |  | 0.80 |
Categories | 3.36±1.77 |  | 3.90±1.86 |  | 0.35 | |
Perseveration | 6.15±5.54 |  | 7.88±9.02 |  | 0.47 |