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Table 1 Demographic and clinical characteristics of study participants before matching

From: Severe sleep disturbance is associated with executive function impairment in patients with first-episode, treatment-naïve major depressive disorders

 

Group 1 (121)

Group 2 (175)

Effect Size

t, z, or Chi-square

P value

Age

41.8 ± 9.2

35.1 ± 10.6

0.675

−5.600 a

< 0.001

Education years (year)

11.9 ± 4.0

13.1 ± 3.7

0.311

2.588 a

0.010

Sex (male) (%)

39 (32.2)

52 (29.7)

0.027

0.213 b

0.645

Occupation (%)

 Full-time or part-time

83 (68.6)

127 (72.6)

   

 Unemployed or retired

38 (31.4)

48 (27.4)

0.043

0.549 b

0.459

Nature of work (%)

 Mental talents labor

58 (47.9)

117 (66.9)

   

 Physical labor

39 (32.2)

33 (18.9)

   

 Both

24 (19.9)

25 (14.3)

0.192

10.924 b

0.004

Marital status (%)

 Married or remarried

101 (83.5)

107 (61.1)

   

 Divorced or widowed or single

20 (16.5)

68 (38.9)

0.240

17.072 b

< 0.001

Living situation (%)

 Living alone

12 (9.9)

15 (8.6)

   

 With parents or spouse

31 (25.6)

66 (37.7)

   

 With spouse and child

9 (7.4)

35 (20.0)

   

 Other

69 (57.1)

59 (33.7)

0.259

19.919 b

< 0.001

Independence (%)

 Independent

115 (95.0)

156 (89.1)

   

 Need assistance

6 (5.0)

19 (10.9)

0.104

3.219 b

0.073

Childhood trauma (%)

 Yes

39 (32.2)

71 (40.6)

0.085

2.131 b

0.144

Religion (%)

 No

117 (96.7)

158 (90.3)

0.123

4.457 b

0.035

Smoking history (%)

 Never

89 (73.6)

136 (77.7)

   

 Quit smoking

11 (9.0)

7 (4.0)

   

 Smoking now

21 (17.4)

32 (18.3)

0.105

3.246 b

0.197

Alcohol use (%)

 Never

89 (73.6)

106 (60.6)

   

 Quit drinking

10 (8.3)

5 (2.8)

   

 Drinking now

22 (18.1)

64 (36.6)

0.220

14.284 c

0.001

Hypertension (%)

 Yes

14 (11.6)

10 (5.7)

0.105

3.293 b

0.070

Diabetes (%)

 Yes

7 (5.8)

4 (2.3)

0.091

2.448 c

0.131

Hyperlipidemia (%)

 Yes

9 (7.4)

18 (10.3)

0.049

0.700 b

0.403

First degree relatives (%)

 Yes

20 (16.5)

33 (18.9)

0.030

0.264 b

0.608

Duration of MDD (months)

6.0 (2.0, 12.0)

6.0 (3.0, 21.0)

 

−1.513 d

0.130

BMI (%)

  

0.144

6.157 b

0.104

 Low weight

11 (9.1)

18 (10.3)

   

 Normal

59 (48.8)

107 (61.1)

   

 Overweight

41 (33.8)

42 (24.0)

   

 Obesity

10 (8.3)

8 (4.6)

   

HAMD anxiety subscale

5.8 ± 2.2

6.1 ± 1.8

0.149

0.972 a

0.332

HAMD weight subscale

0.0 (0.0, 2.0)

0.0 (0.0, 1.0)

 

−3.422 d

0.001

HAMD cognition subscale

3.0 ± 1.9

3.1 ± 1.6

0.057

0.493 a

0.623

HAMD retard subscale

6.8 ± 1.7

6.5 ± 1.8

0.171

− 1.534 a

0.126

HAMA somatic anxiety

13.4 ± 4.1

13.2 ± 3.7

0.051

− 0.544 a

0.687

HAMA psychological anxiety

6.9 ± 4.3

7.5 ± 4.2

0.141

1.182 a

0.238

  1. G1 Group 1, patients with severe sleep disturbance, G2 Group 2, patients without severe sleep disturbance
  2. a Independent sample t-test; b chi-square test; c Fisher’s exact test; d nonparametric test