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Table 2 Demographic and clinical characteristics of PWE according to depression and anxiety

From: A cross-sectional study on the association of serum uric acid levels with depressive and anxiety symptoms in people with epilepsy

Variables

Depressive symptoms

Anxiety symptoms

With depressive symptoms (n=65)

Without depressive symptoms (n=255)

P

With anxiety symptoms (n=82)

Without anxiety symptoms (n=238)

P

SUA (umol/L), mean±SD

288.52 ± 60.05

353.22 ± 95.46

< 0.001a

309.39 ± 83.26

350.65 ± 94.06

< 0.001a

Age (Years), mean±SD

42.77 ± 16.60

36.64 ± 15.56

0.005a

36.77 ± 16.04

38.26 ± 15.92

0.464a

Gender-female, n (%)

38 (58.5)

96 (37.6)

0.002c

47 (57.3)

87 (36.6)

0.001c

BMI (Kg/M2), mean±SD

23.21 ± 3.29

23.55 ± 3.95

0.516a

22.78 ± 3.58

23.73 ± 3.88

0.053a

Marital status-married, n (%)

46 (70.8)

159 (62.4)

0.207c

50 (61.0)

155 (65.1)

0.499c

Educational level, n (%)

  

< 0.001c

  

0.005c

 University and above

10 (15.4)

85 (33.3)

 

15 (18.3)

80 (33.6)

 

 Middle school

40 (61.5)

153 (60.0)

 

53 (64.6)

140 (58.8)

 

 Primary school and below

15 (23.1)

17 (6.7)

 

14 (17.1)

18 (7.6)

 

Residence-rural area, n (%)

24 (36.9)

91 (35.7)

0.853c

33 (40.2)

82 (34.5)

0.346c

Per capita monthly family income (Yuan), n (%)

  

0.026c

  

0.135c

 <1000

12 (18.5)

19 (7.5)

 

11 (13.4)

20 (8.4)

 

 1000–5000

43 (66.2)

187 (73.3)

 

61 (74.4)

169 (71.0)

 

 >5000

10 (15.4)

49 (19.2)

 

10 (12.2)

49 (20.6)

 

Age at onset (Years),median (IQR)

37 (19, 48)

29 (16, 46)

0.085b

29 (18, 45)

30 (18, 47)

0.552b

Disease duration (Years),median (IQR)

2 (1, 7)

2 (1, 6)

0.786b

2 (1, 5)

2 (1,6)

0.557b

Seizure type-focal onset, n (%)

54 (83.1)

212 (83.1)

0.991c

68 (82.9)

198 (83.2)

0.956c

Seizure frequency over the last year, n (%)

  

0.44c

  

0.03c

 Seizure-feee

11 (16.9)

52 (20.4)

 

10 (12.2)

53 (22.3)

 

 1–11

31 (47.7)

133 (52.2)

 

40 (48.8)

124 (52.1)

 

 >12

23 (35.4)

70 (27.5)

 

32 (39.0)

61 (25.6)

 

Treatment-monotherapy, n (%)

57 (87.7)

229 (89.8)

0.622c

73 (89.0)

213 (89.5)

0.905c

>50% nocturnal seizures, n (%)

27 (41.5)

93 (36.5)

0.451c

34 (41.5)

86 (36.1)

0.39c

  1. SUA serum uric acid, BMI body mass index, PWE patients with epilepsy, IQR interquartile range, SD standard deviation
  2. Student’s t testsa, Mann–Whitney U-testsb and Chi-square testsc were used in Table 2