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Table 4 Overview of endocrinological parameters measured from blood samples during three different timepoints

From: Study protocol of comprehensive risk evaluation for anorexia nervosa in twins (CREAT): a study of discordant monozygotic twins with anorexia nervosa

Analysis

Sample 1

Day 1 (T1) 3:30 pm

Sample 2

Day 2

8:00 am

Sample 3

Day 2

10:00 am

Sample type

Hypothalamic–pituitary–adrenal axis

 

 Adrenocorticotropic hormone (ACTH)

X

X

X

Plasma

 Cortisol

X

X

X

Serum

Hypothalamic–pituitary–thyroid axis

 Thyroid-stimulating hormone (TSH)

(X)

X

 

Serum

 Free triiodothyronine (fT3)

(X)

X

 

Serum

 Free thyroxine (fT4)

(X)

X

 

Serum

Hypothalamic–pituitary–gonadal axis

 Follicle stimulating hormone (FSH)

 

X

 

Serum

 Luteinizing hormone (LH)

 

X

 

Serum

 Dehydroepiandrosterone (DHEAS)

 

X

 

Serum

 Sex hormone-binding globulin (SHBG)

 

X

 

Serum

 Testosterone

 

X

 

Serum

Hypothalamic–pituitary–somatotropic axis

 Insulin-like growth factor 1 (IGF-1)

X

X

 

Serum

 Insulin-like growth factor-binding protein 1 (IGFBP-1)

X

X

 

Serum

 Insulin-like growth factor-binding protein 3 (IGFBP-3)

X

X

 

Serum

Gastrointestinal hormones

 Acyl/deacyl-ghrelin

X

X

X

Plasma

Adipokines

 Adiponectin (ADIP)

X

X

X

Serum

 Leptin

 

X

 

Serum

Electrolytes

 Sodium

X

 

X

Plasma

 Sodium

X

 

X

Urine