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Table 2 Comparisons of Inpatient and Emergency Room Admissions and TD Claims Among Patients With ≥10% or ≥ 30% Antipsychotic Dose Reductions vs Controls in the BD and MDD Groups

From: Hospital utilization rates following antipsychotic dose reduction in mood disorders: implications for treatment of tardive dyskinesia

 

Adjusted HR (95% CI)

BD

MDD

 

≥10%

P

≥30%

P

≥10%

P

≥30%

P

Disease-specific admission

1.22 (1.15, 1.31)

< 0.001*

1.24 (1.15, 1.33)

< 0.001*

1.22 (1.11, 1.34)

< 0.001*

1.27 (1.14, 1.41)

< 0.001*

Psychiatric admission

1.19 (1.13, 1.24)

< 0.001*

1.19 (1.13, 1.25)

< 0.001*

1.17 (1.11, 1.23)

< 0.001*

1.16 (1.10, 1.24)

< 0.001*

All-cause IP admission

1.17 (1.12, 1.23)

< 0.001*

1.17 (1.11, 1.24)

< 0.001*

1.11 (1.05, 1.16)

< 0.001*

1.12 (1.06, 1.18)

< 0.001*

All-cause ER visit

1.09 (1.05, 1.13)

< 0.001*

1.10 (1.06, 1.15)

< 0.001*

1.07 (1.02, 1.11)

< 0.01*

1.08 (1.03, 1.13)

< 0.01*

TD claim for all patients

1.45 (0.75, 2.82)

0.27

1.83 (0.87, 3.88)

0.11

2.40 (1.19, 4.83)

0.01*

2.51 (1.14, 5.52)

0.02*

TD claim for patients without baseline TD

1.95 (0.90, 4.22)

0.09

2.11 (0.88, 5.07)

0.09

2.34 (1.05, 5.21)

0.04*

2.90 (1.15, 7.29)

0.02*

  1. BD bipolar disorder, CI confidence interval, ER emergency room, HR hazard ratio, IP inpatient, MDD major depressive disorder, TD tardive dyskinesia. *P < 0.05