Table 1 Patient baseline demographics

Age, years (SD)

43.1 (15.1)

28.8 (4.3)

51.3 (12.7)

< 0.0001^a

Sex, male, n (%)

133 (55.0)

57 (64.0)

76 (49.7)

0.0328^b

Family status, married or in a relationship, n (%)

53 (22.0)

13 (14.8)

40 (26.1)

0.0520^b

Employment status, n (%)

< 0.0001^b

 Employed

43 (18.0)

23 (26.4)

20 (13.2)

 Unemployed

73 (30.5)

36 (41.4)

37 (24.3)

 Annuitant

99 (41.4)

13 (14.9)

86 (56.6)

 Housewife/househusband

11 (4.6)

2 (2.3)

9 (5.9)

 In school/education/re-education

13 (5.4)

13 (15.0)

0 (0.0)

 Duration of untreated psychosis, mean (SD), years

1.2 (8.0)

1.4 (3.2)

1.0 (9.8)

0.7719^a

 Age at diagnosis, mean (SD), years

30.9 (13.0)

23.0 (4.3)

35.3 (14.2)

< 0.0001^a

Time of diagnosis, n (%)

< 0.0001^b

  ≤ 5 years

78 (32.4)

47 (53.4)

31 (20.3)

  > 5 years

163 (67.6)

41 (46.6)

122 (79.7)

Number of illness episodes, n (%)

0.0002^b

  ≤ 5 episodes

137 (57.1); 19 (7.9) of which with first episode of schizophrenia

64 (72.7)

73 (48.0)

  > 5 episodes

103 (42.9)

24 (27.3)

79 (52.0)

 BMI, mean (SD), kg/m²

29.3 (6.9)

28.6 (7.3)

29.7 (6.6)

0.2381^a

 BPRS at baseline, mean (SD)

54.1 (15.6) (n = 228, FAS)

53.0 (16.1) (n = 88, all values)

53.7 (15.9) (n = 151, all values)

0.7608^a

 CGI-S at baseline, mean (SD)

4.8 (0.8) (n = 235, FAS)

4.7 (0.9) (n = 89, all values)

4.8 (0.8) (n = 153, all values)

n/a

 WHO-5 at baseline, mean (SD)

10.6 (5.6) (n = 235, FAS)

11.1 (5.7) (n = 88, all values)

10.5 (5.7) (n = 150, all values)

n/a

 GAF at baseline, mean (SD)

47.0 (13.9) (n = 235, FAS)

49.9 (13.1) (n = 88, all values)

45.6 (14.6) (n = 152, all values)

n/a