Table 1 Characteristics of patients from each of the four study databases
Characteristic | CCAE (N = 114,543) | MDCD (N = 69,006) | MDCR (N = 5660) | Optum (N = 80,459) |
|---|---|---|---|---|
Age at index (years), Mean (SD) | 32.4 (15.6) | 37.9 (25.7) | 74.5 (8.5) | 51.0 (23.5) |
Gender: Female, % | 60.4% | 65.6% | 57.7% | 62.4% |
Charlson comorbidity index scorea, Mean (SD) | 0.5 (1.3) | 1.9 (2.9) | 2.9 (2.6) | 1.7 (2.5) |
Common comorbid conditionsa | ||||
Pain | 46.6% | 58.7% | 68.8% | 59.1% |
Inflammatory disorder of the respiratory system | 33.8% | 38.2% | 31.4% | 33.4% |
Anxiety disorder | 25.7% | 21.3% | 19.8% | 27.3% |
Traumatic injury | 21.6% | 27.4% | 30.8% | 25.4% |
Arthropathy | 20.3% | 29.8% | 51.9% | 35.9% |
Dysthymia | 20.3% | 8.6% | 17.4% | 15.7% |
Inflammatory disorder of digestive system | 20.2% | 24.1% | 18.0% | 19.1% |
Neoplastic disease | 14.8% | 10.2% | 43.6% | 24.3% |
Hyperlipidemia | 13.2% | 23.7% | 58.0% | 38.0% |
Visual system disorder | 12.7% | 31.3% | 52.8% | 31.7% |
Hypertensive disorder | 12.7% | 36.6% | 67.6% | 39.2% |
Malaise and fatigue | 12.3% | 11.9% | 22.5% | 19.2% |
Backache | 10.8% | 16.9% | 20.1% | 17.8% |
Vascular disorder | 8.1% | 19.9% | 45.9% | 24.8% |
Drug dependence | 6.5% | 15.6% | 8.0% | 10.2% |
Osteoarthritis | 5.5% | 16.5% | 34.1% | 19.6% |
Diabetes mellitus | 5.0% | 18.7% | 26.7% | 15.7% |
Other conditions of interest | ||||
Bipolar disorder | 1.1% | 4.3% | 1.1% | 1.5% |
PTSD | 1.8% | 3.2% | 2.2% | 1.7% |
Psychotic disorder | 1.3% | 6.9% | 3.8% | 2.7% |
Obsessive compulsive disorder | 0.8% | 0.5% | 0.5% | 0.7% |
Personality disorder | 0.8% | 1.7% | 1.1% | 0.9% |
Suicidal history | ||||
Suicidal thoughts | 3.9% | 4.3% | 1.0% | 2.9% |
Suicidal deliberate poisoning | 0.2% | 0.2% | 0.0% | 0.2% |