Fig. 4

Antidepressant outcomes in DTMS studies with H1-coil vs. rTMS studies with F8-coil. a. Primary outcome (depression severity): standardised HDRS change score at baseline (pre) – session 10 (post). b. Secondary outcome (response rates at session 10 vs. baseline). c. Secondary outcome (remission rates at session 10 vs. baseline). Note. Figures a-c are forest plots of mixed-effects meta-analyses comparing the antidepressant outcomes in studies with F8-coil vs. H1-coil. In contrast to Fig. 2, each forest plot shows two diamonds corresponding to the pooled mean weighted effects of studies with F8-coil (the upper diamonds) vs. studies with H1-coil (the lower diamonds). Abbreviations: CI, 95% confidence interval; DTMS, deep transcranial magnetic stimulation; F8, figure-of-eight coil (rTMS); H1, H1-coil (DTMS); HDRS, Hamilton depression rating scale; Hedges’ g (effect size), standardised paired difference in means corrected for the sample size; rTMS, repetitive transcranial magnetic stimulation; Total, sample size per study