Table 2 Topics and number of statements issued by each CPG

Screening

1 R

1 R

4R 1 GCP

1 R

1 R

3 R 1 GCP

Diagnosis

1 R

4 R

1 GCP

1 R

1 R 3 GCP

 Pharmacological treatment: general

43 R

35 R^b

8 R 5 GCP

1 R^a

60 R^c

5 R 9 CBR^a

6 R

115 R 15 GCP

 Pharmacological treatment: 1st line

1 R

3 R

6 R

3 R

1 R

7 R

 Pharmacological treatment: 2nd line

1 R

2 R

3 R

1 R

7 R

 Psychological treatment: general

6 R

7 R^b

2 R 1 GCP

1 R^a

21 R^c

3 R 3 CBR^a

5 R

7 R 3 GCP

 Psychological treatment: recommends at least one specific therapy

14R

15 R^b

4 R

9 R

3 R

6 R

5 R

15 R

 Electro-stimulation

9 R

11 R

4 R 2 GCP

16 R

7 R 2 CBR

5 R

20 R 6 GCP

 Acupuncture

1 R

12 R

 St. John’s wort

1 R

1R

1 R 1 GCP

3 R

1 R

2 R

 Light therapy

1 R

1 R

1 R

6 R

 Exercise

1 R

1 R

2 R

1 R

1 R

3 R

 Yoga

1 R

 Sleep deprivation

1 R

 Others treatments

10 R

3 R

4 R

Other statements

18 R

35 R

13 R 3 GCP

89 R

3 R 8 CBR

6 R

1 R

9 R 22 GCP

Total of statements

110 R

12 R

108 R

43 R 14 GCP

1 R^a

211 R^c

25 R 32 CBR

1 R

31 R

7 R

199 R 50 GCP