| Single-drug deaths in England, total n | Single-drug deaths in England, death rate per 100,000 person-years (95% CI) | Single and first listed drug deaths in England, total n | Single and first listed drug deaths in England, Death rate per 100,000 person-years (95% CI) | Prescriptions, average number per year | Prescription rate per 100,000 person-years (95% CI) | Non-fatal self-poisonings in three centres, average number per year | Self-poisoning rate per 100,000, per 100,000 person-years (95% CI) |
---|---|---|---|---|---|---|---|---|
Mood Stabilisers | ||||||||
 Lithium | 6 | 0.002 (0.001–0.004) | 10 | 0.003 (0.001–0.005) | 4956 | 107.24 (106.18–108.30) | 12 | 1.64 (1.32–2.01) |
 Sodium valproate | 15 | 0.004 (0.002–0.007) | 18 | 0.005 (0.003–0.008) | 15,433 | 333.97 (332.11–335.84) | 32 | 4.45 (3.92–5.03) |
 Carbamazepine | 33 | 0.010 (0.007–0.014) | 56 | 0.016 (0.012–0.021) | 18,836 | 407.62 (405.56–409.68) | 28 | 3.87 (3.88–4.42) |
 Lamotrigine | 5 | 0.001 (0.00–0.003) | 12 | 0.004 (0.002–0.006) | 7635 | 165.22 (163.91–166.54) | 15 | 2.02 (1.67–2.43) |
 Total | 59 |  | 96 |  | 46,860 |  | 87 |  |
Antipsychotics | ||||||||
 Chlorpromazine | 12 | 0.004 (0.002–0.006) | 19 | 0.006 (0.003–0.009) | 3760 | 81.37 (80.46–82.30) | 25 | 3.44 (2.97–3.95) |
 Risperidone | 1 | 0.000 (0.00–0.002) | 2 | 0.001 (0.00–0.002) | 8302 | 179.65 (178.29–181.03) | 34 | 4.69 (4.15–5.29) |
 Quetiapine | 40 | 0.012 (0.008–0.016) | 65 | 0.019 (0.015–0.024) | 9971 | 215.78 (214.28–217.28) | 73 | 10.20 (9.39–11.07) |
 Olanzapine | 55 | 0.016 (0.012–0.021) | 78 | 0.023 (0.018–0.029) | 10,568 | 228.70 (227.16–230.25) | 61 | 8.55 (7.81–9.34) |
 Clozapine | 35 | 0.010 (0.007–0.014) | 40 | 0.012 (0.008–0.016) | 157 | 3.39 (3.21–3.59) | 4 | 0.54 (0.36–0.77) |
 Total | 143 |  | 204 |  | 32,758 |  | 197 |  |