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Table 1 Number and rates of suicides involving single-drugs or single and multiple (first-listed) drugs in England and of individuals prescribed each medication, in individuals aged 15 years and over (2005–2012)

From: Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning

  Single-drug deaths in England, total n Single-drug deaths in England, death rate per 100,000 person-years (95% CI) Single and first listed drug deaths in England, total n Single and first listed drug deaths in England, Death rate per 100,000 person-years (95% CI) Prescriptions, average number per year Prescription rate per 100,000 person-years (95% CI) Non-fatal self-poisonings in three centres, average number per year Self-poisoning rate per 100,000, per 100,000 person-years (95% CI)
Mood Stabilisers
 Lithium 6 0.002 (0.001–0.004) 10 0.003 (0.001–0.005) 4956 107.24 (106.18–108.30) 12 1.64 (1.32–2.01)
 Sodium valproate 15 0.004 (0.002–0.007) 18 0.005 (0.003–0.008) 15,433 333.97 (332.11–335.84) 32 4.45 (3.92–5.03)
 Carbamazepine 33 0.010 (0.007–0.014) 56 0.016 (0.012–0.021) 18,836 407.62 (405.56–409.68) 28 3.87 (3.88–4.42)
 Lamotrigine 5 0.001 (0.00–0.003) 12 0.004 (0.002–0.006) 7635 165.22 (163.91–166.54) 15 2.02 (1.67–2.43)
 Total 59   96   46,860   87  
Antipsychotics
 Chlorpromazine 12 0.004 (0.002–0.006) 19 0.006 (0.003–0.009) 3760 81.37 (80.46–82.30) 25 3.44 (2.97–3.95)
 Risperidone 1 0.000 (0.00–0.002) 2 0.001 (0.00–0.002) 8302 179.65 (178.29–181.03) 34 4.69 (4.15–5.29)
 Quetiapine 40 0.012 (0.008–0.016) 65 0.019 (0.015–0.024) 9971 215.78 (214.28–217.28) 73 10.20 (9.39–11.07)
 Olanzapine 55 0.016 (0.012–0.021) 78 0.023 (0.018–0.029) 10,568 228.70 (227.16–230.25) 61 8.55 (7.81–9.34)
 Clozapine 35 0.010 (0.007–0.014) 40 0.012 (0.008–0.016) 157 3.39 (3.21–3.59) 4 0.54 (0.36–0.77)
 Total 143   204   32,758   197