Variables | Patients (n = 181) | Control subjects (n = 320) | P-value |
---|---|---|---|
Age, years | |||
 Mean (SD) | 41.9 (11.1) | 44.6 (12.5) | 0.02a |
Sex, n (%) | |||
 Male | 22 (12) | 197 (62) | <0.0001b |
 Female | 159 (88) | 123 (38) | |
Telomere length | |||
 Mean (SD) | 0.77 (0.12) | 0.81 (0.14) | 0.006a |
BMI, n (%)c | |||
 Underweight | 2 (1.1) |  |  |
 Normal weight | 70 (39) | N/A | N/A |
 Overweight | 56 (31) |  |  |
 Obese | 44 (24) |  |  |
Smoking status, n (%)d | |||
 Yes | 27 (15) | N/A | N/A |
 No | 151 (83) | ||
Alcohol status, n (%)e | |||
 Standard size drinks per week | |||
   < 1 | 100 (55) |  |  |
  1–4 | 54 (30) | N/A | N/A |
   > =5 | 22 (12) |  |  |
Education, n (%)f | |||
 Low | 15 (8) |  |  |
 Middle | 72 (40) | N/A | N/A |
 High | 92 (51) |  |  |
Antidepressants, n (%)g | |||
 Yes | 63 (35) | N/A | N/A |
 No | 102 (56) | ||
Tranquilizers, n (%)h | |||
 Yes | 27 (15) | N/A | N/A |
 No | 131 (72) | ||
Baseline MADRS-S | |||
 Median score (IQR) | 20 (14–25) | N/A | N/A |
Baseline HAD-D | |||
 Median score (IQR) | 8 (6–11) | N/A | N/A |
Baseline HAD-A | |||
 Median score (IQR) | 12 (9–15) | N/A | N/A |
Baseline PHQ-9 | |||
 Median score (IQR) | 13 (9–17) | N/A | N/A |