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Table 7 Cut-off score, sensitivity, specificity, AUC, FNR, FEP, PPV, NPV based on ROC curve analysis to discriminate ASD and TD control, and ASD and non-ASD clinical groups

From: Investigating the validation of the Chinese Mandarin version of the Social Responsiveness Scale in a Mainland China child population

 

Cut-off

Sensitivity

Specificity

AUC

FNR

FPR

PPV

NPV

ASD vs. TD

56.5

0.950

0.900

0.972*

0.050

0.100

0.824

0.974

ASD vs. ADHD

77.5

0.748

0.767

0.821*

0.252

0.233

0.899

0.523

ASD vs. MR

77.5

0.748

0.603

0.692*

0.252

0.397

0.858

0.427

ASD vs. ADHD and MR combined

77.5

0.691

0.748

0.761*

0.309

0.252

0.782

0.648

  1. Note: AUC area under the curve, FNR false-negative rate, FPR false-positive rate, PPV positive-predictive value, NPV negative-predictive value* P < 0.001