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Table 1 Description of the sample

From: Patterns of initiation of second generation antipsychotics for bipolar disorder: a month-by-month analysis of provider behavior

 

Bipolar population (N =170,713) a

Never initiated SGA during study period (N =81,167, 64.1% of those eligible for SGA initiation)

Ever initiated SGA during study period (N =45,389, 35.9% of those eligible for SGA initiation)

Variable

Mean

SD

Mean

SD

Mean

SD

Age at study entry b

50.3

13.3

51.6

13.6

48.3

13.0

 

N

%

N

%

N

%

Gender (female)

24,076

14.1

10,804

13.3

6,954

15.3

Disability status ≥50% c,d

52,584

30.9

23,067

28.5

13,148

29.0

Marital status d

76,315

44.9

34,786

43.3

18,265

40.5

Race/ethnicity e

      

White

127,742

82.2

60,381

83.0

34,425

82.6

African American

20,884

13.4

9,305

12.8

5,588

13.4

Hispanic

4,034

2.6

1,861

2.6

891

2.1

Other race/ethnicityc

2,684

1.7

700

1.0

455

1.1

Clinical/treatment course d

      

Psychotic features

22,119

13.0

6,822

8.4

7,322

16.1

Bipolar type I (versus type II/NOS)f

145,128

85.0

68,344

84.2

40,283

88.8

Antidepressant prescription

139,807

81.9

55,920

68.9

34,969

77.0

Antimanic prescription

128,596

75.3

51,820

63.8

35,755

78.8

Any psychiatric hospitalization

64,117

37.6

23,284

28.7

21,330

47.0

Comorbidities d

      

Diabetes

42,517

24.9

20,679

25.5

10,138

22.3

Obesity

61,182

35.8

27,469

33.8

16,581

36.5

Hyperlipidemia

101,886

59.7

47,770

58.9

26,190

57.7

Substance abuse

79,658

46.7

33,202

40.9

23,280

51.3

Tobacco use disorder

86,311

50.6

37,406

46.1

24,182

53.3

Anxiety disorder

102,130

59.8

43,310

53.4

27,331

60.2

Sleep disorder

29,355

17.2

11,762

14.5

8,072

17.8

Cardiac dysrhythmia

19,600

11.5

9,509

11.7

4,827

10.6

Liver disorder

22,332

13.1

9,460

11.7

5,997

13.2

Kidney disorder

19,044

11.2

9,271

11.4

4,729

10.4

Thyroid disorderc

20,226

11.9

9,429

11.6

5,566

12.3

Traumatic brain injury

9,209

5.4

3,629

4.5

2,557

5.6

  1. aIncludes data on those patients ineligible to be labeled as SGA initiator or SGA non-initiator (N = 44,157).
  2. bUnless otherwise stated, all comparisons between the ever-initiated and never-initiated groups were p < .0001.
  3. cFor these variables, comparison between the ever-initiated and never-initiated groups was p > .0001 (>50% disability status: p = .0385; other race/ethnicity: p = .0120; thyroid disorder, p = .0006).
  4. dUnless otherwise stated, these variables were coded as present if they occurred at any point during the study period.
  5. eBased on smaller N, due to missing values for 9% of the sample.
  6. fAt patient’s last available data during the study period.
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BMC Psychiatry

ISSN: 1471-244X

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