Cutoff points | N (%) | Sensitivity (CI 95%) % | Specificity (CI 95%) % | PPV % | NPV % | Accuracy % | Youden’s index (*) |
---|---|---|---|---|---|---|---|
≥ 1 | 363 (81.2) | 100.0 (91.2 – 100.0) | 20.6 (16.8 – 24.9) | 11.0 (8.0 – 14.7) | 100.0 (95.7 – 100.0) | 60.3 (58.4 – 62.3) | 0.206 |
≥ 2 | 303 (67.8) | 97.5 (86.8 – 99.9) | 35.1 (30.5 – 40.0) | 12.9 (9.3 – 17.2) | 99.3 (96.2 – 100.0) | 66.3 (62.9 – 70.0) | 0.326 |
≥ 3 | 239 (53.5) | 95.0 (83.1 – 99.4) | 50.6 (45.6 – 55.6) | 15.9 (11.5 – 21.2) | 99.0 (96.6 – 99.9) | 72.8 (68.6 – 77.0) | 0.456 |
≥ 4 | 196 (43.8) | 90.0 (76.3 – 97.2) | 60.7 (55.8 – 65.5) | 18.4 (13.2 – 24.5) | 98.4 (96.0 – 99.6) | 75.3 (70.1 – 80.6) | 0.507 |
≥ 5 | 150 (33.6) | 82.5 (67.2 – 92.7) | 71.3 (66.6 – 75.6) | 22.0 (15.7 – 29.5) | 97.6 (95.2 – 99.0) | 76.9 (70.5 – 83.2) | 0.538 |
≥ 6 | 122 (27.3) | 82.5 (67.2 – 92.7) | 78.1 (73.8 – 82.1) | 27.0 (19.4 – 35.8) | 97.8 (95.6 – 99.1) | 80.3 (74.0 – 86.6) | 0.606 |
≥ 7 | 102 (22.8) | 82.5 (67.2 – 92.7) | 83.0 (79.0 – 86.6) | 32.4 (23.4 – 42.3) | 98.0 (95.9 – 99.2) | 82.8 (76.5 – 89.0) | 0.655 |
≥ 8 | 85 (19.0) | 80.0 (64.4 – 90.9) | 87.0 (83.3 – 90.1) | 37.6 (27.4 – 48.8) | 97.8 (95.7 – 99.0) | 83.5 (77.0 – 90.0) | 0.670 |
≥ 9 | 67 (15.0) | 72.5 (56.1 – 85.4) | 90.7 (87.4 – 93.3) | 43.3 (31.2 – 56.0) | 97.1 (94.9 – 98.5) | 81.6 (74.4 – 88.7) | 0.632 |
≥10 | 61 (13.6) | 70.0 (53.5 – 83.4) | 91.9 (88.8 – 94.4) | 45.9 (33.1 – 59.2) | 96.9 (94.6 – 98.4) | 80.9 (73.6 – 88.3) | 0.619 |
≥ 11 | 53 (11.9) | 65.0 (48.3 – 79.4) | 93.4 (90.5 – 95.6) | 49.1 (35.1 – 63.2) | 96.4 (94.1 – 98.0) | 79.2 (71.6 – 86.8) | 0.584 |
≥ 12 | 43 (9.6) | 55.0 (38.5 – 70.7) | 94.8 (92.2 – 96.8) | 51.2 (35.5 – 66.7) | 99.5 (93.0 – 97.3) | 74.9 (67.0 – 82.8) | 0.498 |
≥ 13 | 33 (7.4) | 47.5 (31.5 – 63.9) | 96.6 (94.3 – 98.1) | 57.6 (39.2 – 74.5) | 94.9 (92.4 – 96.8) | 72.0 (64.1 – 79.9) | 0.441 |
≥ 14 | 29 (6.5) | 45.0 (29.3 – 61.5) | 97.3 (95.2 – 98.6) | 62.1 (42.3 – 79.3) | 94.7 (92.1 – 96.7) | 71.1 (63.3 – 79.0) | 0.423 |
≥ 15 | 23 (5.1) | 35.0 (20.6 – 51.7) | 97.8 (95.8 – 99.0) | 60.9 (38.5 – 80.3) | 93.9 (91.1 – 96.0) | 66.4 (58.9 – 73.9) | 0.328 |
≥ 16 | 18 (4.0) | 25.0 (12.7 – 41.2) | 98.0 (96.2 – 99.1) | 55.6 (30.8 – 78.5) | 93.0 (90.2 – 95.2) | 61.5 (54.7 – 68.3) | 0.230 |
≥ 17 | 15 (3.4) | 22.5 (10.8 – 38.5) | 98.5 (96.8 – 99.5) | 60.0 (32.3 – 83.7) | 92.8 (90.0 – 95.1) | 60.5 (53.9 – 67.1) | 0.210 |
≥ 18 | 12 (2.7) | 20.0 (9.1 – 35.6) | 99.0 (97.5 – 99.7) | 66.7 (34.9 – 90.1) | 92.6 (89.8 – 94.9) | 59.5 (53.2 – 65.8) | 0.190 |
≥ 19 | 10 (2.2) | 17.5 (7.3 – 32.8) | 99.3 (97.9 – 99.8) | 70.0 (34.8 – 93.3) | 92.4 (89.6 – 94.7) | 58.4 (52.4 – 64.4) | 0.168 |
≥ 20 | 10 (2.2) | 17.5 (7.3 – 32.8) | 99.3 (97.9 – 99.8) | 70.0 (34.8 – 93.3) | 92.4 (89.6 – 94.7) | 58.4 (52.4 – 64.4) | 0.168 |
≥ 21 | 7 (1.6) | 12.5 (4.2 – 26.8) | 99.5 (98.2 – 99.9) | 71.4 (29.0 – 96.3) | 92.0 (89.1 – 94.4) | 56.0 (50.8 – 61.2) | 0.120 |
≥ 22 | 6 (1.3) | 12.5 (4.2 – 26.8) | 99.8 (98.6 – 100) | 83.3 (35.9 – 99.6) | 92.1 (89.1 – 94.4) | 56.1 (50.9 – 61.3) | 0.123 |
≥ 23 | 4 (0.9) | 10.0 (2.8 – 23.7) | 100.0 (99.1 – 100.0) | 100.0 (39.8 – 100.0) | 91.9 (88.9 - 94.2) | 55.0 (50.3 - 59.7) | 0.100 |