A controlled trial of the Litebook light-emitting diode (LED) light therapy device for treatment of Seasonal Affective Disorder (SAD)

Table 1 SIGH-SAD Outcome Measures at Randomization and after 1, 2, 3 and 4 weeks of treatment.

	Mean SIGH SAD score*		Mean SIGH SAD score As % of randomization score			% Participants in remission (SIGH SAD <9)
	Active	Control	Active	Control	p value	Active	Control	p value
Randomization	28.0 ± 5.3	25.1 ± 3.2	-	-	-	-	-	-
Week 1	18.6 ± 7.9	19.0 ± 7.2	67.1 ± 26.7	74.0 ± 22.5	0.527	7.1	11.1	0.999
Week 2	14.9 ± 10.0	17.9 ± 4.9	54.5 ± 36.4	71.7 ± 19.5	0.208	28.6	0.0	0.127
Week 3	11.1 ± 10.1	14.9 ± 4.2	39.0 ± 30.7	54.4 ± 17.9	0.080	42.9	11.1	0.176
Week 4	8.7 ± 8.4	13.4 ± 5.4	29.9 ± 25.4	54.4 ± 21.8	0.027**	57.1	11.1	0.040***

Notes: Observed cases analysis: for active treatment n = 14 and for placebo treatment n = 9. * interaction of time and treatment significant in repeated measures ANOVA as noted in text. ** comparison significant at p ≤ 0.05 by t test. *** comparison significant at p ≤ 0.05 by Fisher's exact test.

ISSN: 1471-244X