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Table 4 Cognitive measures

From: Sleep architecture and cognitive changes in olanzapine-treated patients with depression: A double blind randomized placebo controlled trial

Cognitive measures

Placebo

Olanzapine

Baseline

Day 2-4

Day 28-31

Baseline

Day 2-4

Day 28-31

ANOVA

Mean ± SD

Mean ± SD

SWM

       

 Between errors

23 ± 26

22 ± 23

12 ± 15

34 ± 24

31 ± 19

21 ± 21

p = .778

 Strategy score

29 ± 8.4

29 ± 7.6

28 ± 7.8

31 ± 8.0

30 ± 7.0

31 ± 6.9

p = .562

RTI

       

 Reaction time

410 ± 80.6

395 ± 43.3

405 ± 52

410 ± 110

380 ± 92.8

388 ± 111

p = .333

 Movement time

579 ± 110

567 ± 104

539 ± 61

542 ± 132

563 ± 136

530 ± 107

p = .395

SSP

5.8 ± 1.4

5.7 ± 1.6

5.6 ± 1.6

5.4 ± 1.4

5.4 ± 1.2

5.7 ± 1.4

p = .296

  1. The mean ± standard deviation (SD) of cognitive measures for both olanzapine and placebo treated group.SWM = Spatial Working Memory task, RTI = Reaction Time task, SSP = Spatial Span task. P value reported for the interaction (time by treatment) of a two-way repeated measures ANOVA.