Comparative efficacy of Concerta
(18, 36 mg) and Ritalin LA
(20 mg) versus placebo in a laboratory school study. Figure shows change from pre-dose baseline in SKAMP-Attention score over time. In the first 4 hours post-dose, Ritalin LA® (20 mg) resulted in significantly greater improvements from baseline than Concerta® (18 mg) in SKAMP-Attention (p = 0.015). Originally published by Springer and Adis Data Information BV/Paediatr Drugs, volume 5, 2003, 545–555, Comparative efficacy of two once daily methylphenidate formulations (Ritalin LA and Concerta) and placebo in children with attention deficit hyperactivity disorder across the school day, Lopez F, et al., Figure 3, ©Adis Data Information BV 2003; with kind permission from Springer Science + Business Media B.V. SKAMP, Swanson, Kotkin, Atkins, M-Flynn, Pelham rating scale.