Table 1 DSM-IV melancholia (low-CORE, high-CORE) inpatients compared to inpatients with psychotic depression (CORE scores >12)
From: Should psychomotor disturbance be an essential criterion for a DSM-5 diagnosis of melancholia?
Melancholia CORE 0 to 10 (N = 18) | Melancholia CORE 15 to 31 (N = 14) | Psychotic CORE 13 to 37 (n = 32) | |
|---|---|---|---|
Sex ratio | 14 F : 4 M | 9 F : 5 M | 18 F : 14 M |
Age (mean) | 74.7 years | 77.4 years | 75.0 years |
Age range | 69–85 years | 67–91 years | 65–87 years |
Age of onset (mean) | 49.8 years | 65.4 years | 56.2 years |
Onset age 65+ | 41% | 79% | 53% |
Duration (mean) | 35 weeks | 49 weeks | >50 weeks |
Hamilton-17 (mean) | 25.9 | 29.1 | 27.8 |
BAS (mean) | 17.2 | 18.6 | 17.4* |
MMSE | 26.6 | 26.9 | 26.7* |
Had depression previously | 89% | 64% | 77% |
Had antidepressants before | 78% | 64% | 77% |
Had E.C.T. previously | 67% | 50% | 68% |
Stress as precipitant | 89% + | 57% | 52% |
Diurnal variation (worse in a.m.: moderate/severe) | 61% + | 36% | 10% |
Unvarying depression | 22% + | 79% | 100% |
Worthlessness | 61% + (4/10 with score <8; 7/8 with score 8–10) | 86% | 74% |
Punishment felt to be deserved | 0% | 29% (4/14) | 52% |