From: Association study of OPRM1 polymorphisms with Schizophrenia in Han Chinese population
SNP | Haplotype/Allele | All | Male | Female | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Cases | OR (95%) | P value | Controls | Cases | OR (95%) | P value | Controls | Cases | OR (95%) | P value | ||
rs799971 | AA | 68 | 132 | 1.00(referent) | 31 | 93 | 1.00(referent) | 37 | 39 | 1.00(referent) | |||
AG | 133 | 102 | 0.417(0.281-0.618) | <0.00001 | 85 | 50 | 0.208(0.121-0.358) | <0.00001 | 48 | 52 | 1.063(0.582-1.941) | 0.84 | |
GG | 63 | 30 | 0.257(0.152-0.436) | <0.00001 | 30 | 11 | 0.127(0.057-0286) | <0.0.00001 | 33 | 19 | 0.564(0.273-1.164) | 0.12 | |
A | 269 | 366 | 1.00(referent) | 147 | 236 | 1.00(referent) | 122 | 130 | 1.00(referent) | ||||
G | 259 | 162 | 0.46(0.357-0.59) | <0.00001 | 145 | 72 | 0.309(0.218-0.439) | <0.00001 | 114 | 90 | 0.741(0.511-1.073) | 0.11 | |
HWE(P) | 0.9 | 0.14 | 0.4 | 1.00 | 0.37 | 0.68 | |||||||
rs2075572 | CC | 140 | 166 | 1.00(referent) | 79 | 84 | 1.00(referent) | 61 | 82 | 1.00(referent) | |||
CG | 100 | 82 | 0.697(0.481-1.010) | 0.06 | 51 | 55 | 1.053(0.643-1.725) | 0.84 | 49 | 27 | 0.383(0.213-0.689) | 0 | |
GG | 24 | 16 | 0.594(0.301-1.171) | 0.59 | 16 | 15 | 0.951(0.437-2.071) | 0.9 | 8 | 1 | 0.087(0.01-0.723) | 0.02 | |
C | 380 | 414 | 1.00(referent) | 209 | 223 | 1.00(referent) | 171 | 191 | 1.00(referent) | ||||
G | 148 | 114 | 0.707(0.534-0.937) | 0.02 | 83 | 85 | 0.96(0.672-1.371) | 0.82 | 65 | 29 | 0.399(0.246-0.648) | <0.00001 | |
HWE(P) | 0.32 | 0.68 | 0.96 | 0.91 | 0.56 | 0.68 | |||||||
rs648893 | CC | 107 | 116 | 1.00(referent) | 55 | 69 | 1.00(referent) | 52 | 47 | 1.00(referent) | |||
CT | 113 | 110 | 0.888(0.61-1.292) | 0.54 | 59 | 57 | 0.755(0.453-1.259) | 0.28 | 54 | 53 | 1.102(0.631-1.925) | 0.73 | |
TT | 44 | 38 | 0.76(0.455-1.268) | 0.29 | 32 | 28 | 0.671(0.36-1.253) | 0.21 | 12 | 10 | 0.848(0.331-2.171) | 0.73 | |
C | 327 | 342 | 1.00(referent) | 169 | 195 | 1.00(referent) | 158 | 147 | 1.00(referent) | ||||
T | 201 | 186 | 0.885(0.689-1.137) | 0.34 | 123 | 113 | 0.796(0.573-1.105) | 78 | 73 | 1.006(0.681-1.486) | 0.98 | ||
HWE(P) | 0.13 | 0.06 | 0.96 | 0.84 | 0.38 | 0.21 | |||||||
rs671531 | AA | 102 | 109 | 1.00(referent) | 56 | 68 | 1.00(referent) | 46 | 41 | 1.00(referent) | |||
AG | 116 | 122 | 0.968(0.665-1.408) | 0.87 | 63 | 69 | 0.893(0.544-1.465) | 0.65 | 53 | 53 | 1.091(0.613-1.942) | 0.77 | |
GG | 46 | 33 | 0.628(0.37-1.065) | 0.09 | 27 | 17 | 0.482(0.237-0.981) | 0.04 | 19 | 16 | 0.902(0.406-2.004) | 0.8 | |
A | 320 | 340 | 1.00(referent) | 175 | 205 | 1.00(referent) | 145 | 135 | 1.00(referent) | ||||
G | 208 | 188 | 0.851(0.663-1.092) | 0.2 | 117 | 103 | 0.752(0.539-1.048) | 0.09 | 91 | 85 | 1.003(0.688-1.463) | 0.99 | |
HWE(P) | 0.2 | 0.08 | 0.95 | 1.00 | 0.67 | 1.00 |