| 1994 - 1997 | 1998 - 2001 | 2002 - 2005 | 2006 - 2009 | Overall | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | ||
Number of patients | 248 | Â | 454 | Â | 711 | Â | 832 | Â | 2246 | Â | |
Number of patients monotherapy | 53 | 21.4 | 99 | 21.8 | 85 | 12.0 | 97 | 11.7 | 334 | 14.9 | |
Number of patients combination therapy | 195 | 78.6 | 355 | 78.2 | 626 | 88.0 | 735 | 88.3 | 1912 | 85.1 | |
Antidepressants | monotherapy | 33 | 13.3 | 54 | 11.9 | 41 | 5.8 | 43 | 5.2 | 171 | 7.6 |
 | combination therapy | 172 | 69.4 | 317 | 69.8 | 531 | 74.7 | 634 | 76.2 | 1655 | 73.7 |
Antipsychotics | monotherapy | 8 | 3.2 | 16 | 3.5 | 16 | 2.3 | 30 | 3.6 | 70 | 3.1 |
 | combination therapy | 97 | 39.1 | 194 | 42.7 | 418 | 58.8 | 534 | 64.2 | 1244 | 55.4 |
Anticonvulsants | monotherapy | 6 | 2.4 | 16 | 3.5 | 15 | 2.1 | 14 | 1.7 | 51 | 2.3 |
 | combination therapy | 65 | 26.2 | 177 | 39.0 | 402 | 56.5 | 425 | 51.1 | 1069 | 47.6 |
Lithium | monotherapy | 6 | 2.4 | 13 | 2.9 | 13 | 1.8 | 10 | 1.2 | 42 | 1.9 |
 | combination therapy | 105 | 42.3 | 152 | 33.5 | 204 | 28.7 | 275 | 33.1 | 736 | 32.8 |