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Table 3 Psychological and Clinical correlates of Major Depressive Disorder

From: Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda

 

Number in study (N,%)

Major depressive disorder (n,%)

Unadjusted OR

(95% CI)

Adjusted OR§

(95% CI)

Negative Coping Style index

  

P = 0.002

P = 0.008

   Low

101 (16.3)

4 (4.0)

1

1

   Medium

322 (52.1)

20 (6.2)

1.61 (0.54-4.81)

1.55 (0.51-4.68)

   High

195 (31.6)

26 (13.3)

3.73 (1.26-11.01)

3.16 (1.06-9.43)

Past Psychiatric history

  

P = 0.516

P = 0.570

   Present

16 (2.6)

2 (12.5)

1.65 (0.36-7.47)

1.56 (0.33-7.28)

Family history of psychiatric illness

  

P = 0.003

P = 0.003

   Present

120 (19.6)

18 (15.0)

2.54 (1.37-4.71)

2.57 (1.37-4.83)

Neurocognitive Impairment

  

P = 0.531

P = 0.535

   Present

396 (64.1)

30 (7.6)

0.83 (0.0.46-1.50)

0.83 (0.45-1.51)

Psychosocial Impairment

  

P = 0.003

P = 0.003

   Present

318 (51.5)

36 (72.0)

2.61 (1.38-4.94)

2.65 (1.39-5.06)

Life-time attempted suicide

  

P < 0.001

P < 0.001

   Present

24 (3.9)

13 (26.0)

17.79 (7.46-42.43)

17.51 (6.94-44.11)

Post traumatic Stress disorder

  

P < 0.001

P < 0.001

   Present

10 (1.6)

8 (80.0)

53.91 (11.09-261.9)

43.76 (8.62-222.09)

Generalized anxiety disorder

  

P = 0.001

P = 0.001

   Present

5 (0.81)

4 (80.0)

49.30 (5.40-450.3)

61.90 (5.90-649.0)

Alcohol dependency disorder

  

P = 0.015

P = 0.003

   Present

4 (0.65)

2 (50.0)

11.79 (1.62-85.57)

24.35 (3.00-197.7)

Most Recent CD4 count (cells/μL)

  

P = 0.413

P = 0.555

   < 100

66 (12.5)

4 (6.1)

1

1

   100-249

159 (30.2)

11 (6.9)

1.15 (0.35-3.76)

1.14 (0.34-3.80)

   250-349

81 (15.4)

7 (8.6)

1.47 (0.41-5.24)

1.39 (0.38-5.11)

   350+

220 (35.6)

19 (8.6)

1.46 (0.48-4.47)

1.35 (0.43-4.24)

BMI Index

  

P = 0.550

P = 0.288

   Underweight

55 (9.2)

4 (7.3)

1

1

   Normal

387 (64.9)

36 (9.3)

1.33 (0.46-3.89)

1.07 (0.36-3.22)

   Overweight

119 (20.0)

6 (5.0)

0.70 (0.19-2.60)

0.52 (0.13-1.97)

   Obese

35 (5.9)

3 (8.6)

1.22 (0.26-5.80)

0.86 (0.17-4.30)

  1. §Adjusted for sex and age