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Table 2 Bipolar disorder medications (ITT population)

From: Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms

OL Baseline

 

Total

(N = 162)

Baseline

Depressive

Symptoms

(n = 59)

Baseline

Manic/Mixed Symptoms

(n = 103)

Number of bipolar medications a, b

   0

17 (10.5)

5 (8.5)

12 (11.7)

   1

37 (22.8)

14 (23.7)

23 (22.3)

   2

49 (30.3)

16 (27.1)

33 (32.0)

   ≥3

59 (36.4)

24 (40.7)

35 (34.0)

Mood stabilizers

128 (79.0)

44 (74.6)

84 (81.6)

Antipsychotics

47 (29.0)

17 (28.8)

30 (29.1)

Antidepressants

48 (29.6)

26 (44.1)

22 (21.4)

Anxiolytics

54 (33.3)

20 (33.9)

34 (33.0)

OL Week 16 (Completers)

 

Total

(N = 120)

Baseline

Depressive

Symptoms

(n = 44)

Baseline

Manic or Mixed Symptoms

(n = 76)

Number of bipolar disorder medications a, c

   0

8 (6.7)

0 (0)

8 (10.5)

   1

41 (34.2)

16 (36.4)

25 (32.9)

   2

39 (32.5)

17 (38.6)

22 (29.0)

   ≥3

32 (26.7)

11 (25.0)

21 (27.6)

Mood stabilizers

99 (82.5)

35 (79.6)

64 (84.2)

Antidepressants

51 (42.5)

28 (63.6)

23 (30.3)

Anxiolytics

32 (26.7)

11 (25.0)

21 (27.6)

  1. ITT, intent to treat; OL, open-label.
  2. aA subject taking > 1 medication within a class and subclass was counted once within the class and subclass.
  3. bClasses included mood stabilizers, antidepressants, antipsychotics, and anxiolytics.
  4. cClasses included mood stabilizers, antidepressants, and anxiolytics.