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Geriatric psychiatry and cognitive disorders

This section incorporates all areas of geriatric psychiatry. Topics of interest include, but are not limited to, dementia, geriatric depression, cognitive impairment, delirium


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  1. The majority of people with dementia have behavioral and psychological symptoms of dementia (BPSD), including depression, anxiety and agitation. These may be elicited or aggravated by disrupted circadian rhyth...

    Authors: Eirin Kolberg, Gunnhild Johnsen Hjetland, Eirunn Thun, Ståle Pallesen, Inger Hilde Nordhus, Bettina S. Husebo and Elisabeth Flo-Groeneboom

    Citation: BMC Psychiatry 2021 21:377

    Content type: Research article

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  2. Frontal variant frontotemporal dementia is a common cause of presenile dementia. A hexanucleotide expansion on chromosome 9 has recently been recognized as the most common genetic mutation cause of this illnes...

    Authors: A. M. Burhan, U. C. Anazodo, N. M. Marlatt, L. Palaniyappan, M. Blair and E. Finger

    Citation: BMC Psychiatry 2021 21:331

    Content type: Case report

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  3. Parkinsonian symptoms are common adverse effects of antipsychotics. Older adults are particularly vulnerable to drug-induced parkinsonism. Nonetheless, parkinsonian symptoms in seniors treated with antipsychot...

    Authors: Anastasios Politis, Nikolaos Kokras, Michael Souvatzoglou, Kostas Siarkos, Panagiotis Toulas, Constantin Potagas, Theodoros Hatzipanagiotou, Georgios Limouris and Panagiotis Alexopoulos

    Citation: BMC Psychiatry 2021 21:289

    Content type: Case report

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  4. Greater cognitive performance has been shown to be associated with better mental and physical health and lower mortality. The present study contributes to the existing literature on the linkages of self-percei...

    Authors: T. Muhammad, Shobhit Srivastava and T. V. Sekher

    Citation: BMC Psychiatry 2021 21:256

    Content type: Research article

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  5. Lichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses. Clonazepam, a commonly used drug for the treatment of anxiety-related disorders and seizures, is known to be an unli...

    Authors: Hee Won Yang, Jong Bin Bae, Jung-Im Na and Ki Woong Kim

    Citation: BMC Psychiatry 2021 21:125

    Content type: Case report

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  6. Several fMRI studies found hyperactivity in the hippocampus during pattern separation tasks in patients with Mild Cognitive Impairment (MCI; a prodromal stage of Alzheimer’s disease). This was associated with ...

    Authors: Katharina Klink, Urs Jaun, Andrea Federspiel, Marina Wunderlin, Charlotte E. Teunissen, Claus Kiefer, Roland Wiest, Frank Scharnowski, Ronald Sladky, Amelie Haugg, Lydia Hellrung and Jessica Peter

    Citation: BMC Psychiatry 2021 21:87

    Content type: Study protocol

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  7. The purpose of this study was to examine if satisfaction with care differs among older trauma patients with and without preexisting mental illness (PMI+/PMI-).

    Authors: Constance McGraw, Jennifer Pekarek, Diane Redmond, Rebecca Vogel, Allen Tanner II and David Bar-Or

    Citation: BMC Psychiatry 2021 21:67

    Content type: Research article

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  8. Major depressive disorders rank in the top ten causes of ill health in all but four countries worldwide and are the leading cause of years lived with disability in Europe (WHO). Recent research suggests that n...

    Authors: Louise Emsell, Maarten Laroy, Margot Van Cauwenberge, Thomas Vande Casteele, Kristof Vansteelandt, Koen Van Laere, Stefan Sunaert, Jan Van den Stock, Filip Bouckaert and Mathieu Vandenbulcke

    Citation: BMC Psychiatry 2021 21:64

    Content type: Study protocol

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  9. Evidence concerning the association between body mass index (BMI) and cognitive function among older people is inconsistent. This study aimed to investigate gender and age as moderators in association between ...

    Authors: Yemin Yuan, Jie Li, Nan Zhang, Peipei Fu, Zhengyue Jing, Caiting Yu, Dan Zhao, Wenting Hao and Chengchao Zhou

    Citation: BMC Psychiatry 2021 21:54

    Content type: Research article

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  10. Major depressive disorder and associated mood syndromes are amongst the most common psychiatric disorders. To date, electroconvulsive therapy (ECT) is considered the most effective short-term treatment for pat...

    Authors: Fangyue Chen, Emad Sidhom, Sharon Yang, Eladia Ruiz-Mendoza and Julius Essem

    Citation: BMC Psychiatry 2021 21:50

    Content type: Case report

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  11. To explore the mutual relationship between multimorbidity, mental illness and frailty, we have set-up the Multimorbidity and Mental health Cohort Study in FRAILty and Aging (MiMiCS-FRAIL) cohort. At the popula...

    Authors: Ivan Aprahamian, Ronei Luciano Mamoni, Nilva Karla Cervigne, Taize Machado Augusto, Carla Vasconcelos Romanini, Marina Petrella, Daniele Lima da Costa, Natalia Almeida Lima, Marcus K. Borges and Richard C. Oude Voshaar

    Citation: BMC Psychiatry 2020 20:573

    Content type: Study protocol

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  12. Mild cognitive impairment (MCI) often presages the development of Alzheimer’s disease (AD). Accurate and early identification of cognitive impairment will substantially reduce the burden on the family and alle...

    Authors: Szabolcs Garbóczy, Éva Magócs, Gergő József Szőllősi, Szilvia Harsányi, Anikó Égerházi and László Róbert Kolozsvári

    Citation: BMC Psychiatry 2020 20:571

    Content type: Research article

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  13. Although adult attention-deficit/hyperactivity disorder has recently gained increased attention, few reports on attention-deficit/hyperactivity disorder in the pre-elderly or elderly have been published. Here,...

    Authors: Hiroyuki Sasaki, Tadashi Jono, Ryuji Fukuhara, Seiji Yuki, Tomohisa Ishikawa, Shuken Boku and Minoru Takebayashi

    Citation: BMC Psychiatry 2020 20:550

    Content type: Case report

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  14. Depression is prevalent but poorly recognized in the Emergency Department (ED). We aimed to identify the frequency of unrecognized geriatric depression and its possible determinants in the ED using the 15-item...

    Authors: Roshana Shrestha, Anmol Purna Shrestha, Abha Shrestha and Barbara Kamholz

    Citation: BMC Psychiatry 2020 20:533

    Content type: Research article

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  15. Bereavement is the experience of an individual following the death of a person of significance to the individual, most often referring to the spouse. Increased morbidity, health care utilization, and mortality...

    Authors: Zhuo Chen, Jiahui Ying, Justin Ingles, Donglan Zhang, Janani Rajbhandari-Thapa, Ruoxi Wang, Kerstin Gerst Emerson and Zhanchun Feng

    Citation: BMC Psychiatry 2020 20:514

    Content type: Research article

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  16. Teams delivering crisis resolution services for people with dementia and their carers provide short-term interventions to prevent admission to acute care settings. There is great variation in these services ac...

    Authors: Jennifer Yates, Miriam Stanyon, David Challis, Donna Maria Coleston-Shields, Tom Dening, Juanita Hoe, Kaanthan Jawahar, Brynmor Lloyd-Evans, Esme Moniz-Cook, Fiona Poland, Amy Streater, Emma Trigg and Martin Orrell

    Citation: BMC Psychiatry 2020 20:505

    Content type: Research article

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  17. In the absence of a cure or effective treatment for dementia, attention has shifted towards identifying risk factors for prevention. Subjective Cognitive Decline (SCD) describes self-perceived worsening of cog...

    Authors: Marco Schlosser, Harriet Demnitz-King, Tim Whitfield, Miranka Wirth and Natalie L. Marchant

    Citation: BMC Psychiatry 2020 20:500

    Content type: Research article

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  18. Cognitive tests currently used in healthcare and research settings do not account for bias in performance that arises due to cultural context. At present there are no universally accepted steps or minimum crit...

    Authors: Waquas Waheed, Nadine Mirza, Muhammed Wali Waheed, Abid Malik and Maria Panagioti

    Citation: BMC Psychiatry 2020 20:492

    Content type: Research article

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  19. Old-age dementias are known to disproportionally affect women as well as individuals with low educational attainment. The higher lifetime risk of dementia among women is usually attributed to their longer life...

    Authors: Caroline Hasselgren, Hans Ekbrand, Björn Halleröd, Madeleine Mellqvist Fässberg, Anna Zettergren, Lena Johansson, Ingmar Skoog and Lotta Dellve

    Citation: BMC Psychiatry 2020 20:434

    Content type: Research article

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  20. Bullous pemphigoid (BP) is an autoimmune blistering skin disease that takes a profound physical and mental toll on those affected. The aim of the study was to investigate the bidirectional association between ...

    Authors: Marianna Rania, Liselotte Vogdrup Petersen, Michael Eriksen Benros, Zhi Liu, Luis Diaz and Cynthia M. Bulik

    Citation: BMC Psychiatry 2020 20:411

    Content type: Research article

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    The Correction to this article has been published in BMC Psychiatry 2020 20:432

  21. Variation in genes implicated in homocysteine and lipid metabolism systems may influence antidepressant response for patients with major depressive disorder (MDD). This study aimed to investigate whether assoc...

    Authors: Baoyu Yuan, Xiaoyan Sun, Zhi Xu, Mengjia Pu, Yonggui Yuan and Zhijun Zhang

    Citation: BMC Psychiatry 2020 20:408

    Content type: Research article

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  22. Research with persons with dementia is important to better understand the causes of dementia and to develop more effective diagnostics, therapies, and preventive measures. Advance Research Directives (ARDs) ha...

    Authors: Karin Jongsma, Julia Perry, Silke Schicktanz and Katrin Radenbach

    Citation: BMC Psychiatry 2020 20:360

    Content type: Research article

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  23. Postoperative delirium is a common complication following major surgeries, leading to a variety of adverse effects. However, there is a paucity of literatures studying the incidence and risk factors associated...

    Authors: Qinfeng Yang, Jian Wang, Xusheng Huang, Yichuan Xu and Yang Zhang

    Citation: BMC Psychiatry 2020 20:343

    Content type: Research article

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  24. We recently reported that older patients with schizophrenia (SZ) show possible idiopathic normal pressure hydrocephalus (iNPH) more frequently than the general population. In this study, we estimated the preva...

    Authors: Yuta Yoshino, Taku Yoshida, Hideo Morino, Masayuki Nakamura, Masao Abe, Hokuto Omachi, Saori Inoue, Yukiyo Miyoshi, Yumina Tachibana, Noriko Yamauchi, Naoya Takeda, Mutsuhiko Mizobuchi, Yuki Ozaki, Shinichiro Ochi, Junichi Iga and Shu-ichi Ueno

    Citation: BMC Psychiatry 2020 20:273

    Content type: Research article

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  25. Depressive symptoms (DS) are a well-recognized public health problem across the world. There is limited evidence with regard to DS and its associates, such as socio-demographic characteristics, lifestyle facto...

    Authors: Uday Narayan Yadav, Tarka Bahadur Thapa, Sabuj Kanti Mistry, Roshan Pokhrel and Mark Fort Harris

    Citation: BMC Psychiatry 2020 20:261

    Content type: Research article

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  26. The long-term prognosis after cognitive behavioral therapy (CBT) in outpatient groups for panic disorder and agoraphobia is not well known. The purpose of this study was to assess long-term outcomes in terms o...

    Authors: Truls Bilet, Torbjørn Olsen, John Roger Andersen and Egil W. Martinsen

    Citation: BMC Psychiatry 2020 20:259

    Content type: Research article

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  27. Cognitive impairment is accompanied with high rates of comorbid conditions, leading ultimately to death. Few studies examine the relation between cognitive transition and mortality, especially in Asian populat...

    Authors: Mu-Cyun Wang, Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, Chih-Hsueh Lin, Wen-Yuan Lin, Chuan-Wei Yang, Shing-Yu Yang and Cheng-Chieh Lin

    Citation: BMC Psychiatry 2020 20:203

    Content type: Research article

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  28. The Holocaust was one of the most traumatic catastrophes in recorded human history. Survivors seeking psychotherapeutic help today, now in their seventies and older, often show symptoms of a posttraumatic stre...

    Authors: Simon Forstmeier, Elisheva van der Hal, Martin Auerbach, Andreas Maercker and Danny Brom

    Citation: BMC Psychiatry 2020 20:186

    Content type: Study protocol

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  29. Delirium is a serious and distressing neurocognitive disorder of physiological aetiology that is common in advanced cancer. Understanding of delirium pathophysiology is largely hypothetical, with some evidence...

    Authors: Ingrid Amgarth-Duff, Annmarie Hosie, Gideon Caplan and Meera Agar

    Citation: BMC Psychiatry 2020 20:182

    Content type: Research article

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  30. Agitation is common in geriatric patients with cognitive impairment, e.g. in persons with dementia (PWD), who are admitted to an emergency department (ED). It might be a first sign of upcoming delirium and is ...

    Authors: Lisa Kroll, Nikolaus Böhning, Heidi Müßigbrodt, Maria Stahl, Pavel Halkin, Birgit Liehr, Christine Grunow, Borjana Kujumdshieva-Böhning, Christian Freise, Werner Hopfenmüller, Wolfgang Friesdorf, Maria Jockers-Scherübl and Rajan Somasundaram

    Citation: BMC Psychiatry 2020 20:165

    Content type: Research article

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  31. Alzheimer’s disease (AD) is a neurodegenerative disorder featuring the behavioral and psychological symptoms of dementia. Patients with early-onset AD that exhibits first as psychotic symptoms usually lack obv...

    Authors: Xiao Li, Zhenzhen Xiong, Yaya Liu, Yiwen Yuan, Junfeng Deng, Weiyi Xiang and Zhe Li

    Citation: BMC Psychiatry 2020 20:128

    Content type: Case report

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  32. Previous studies have demonstrated an association between DNA methylation-based measures of accelerated ageing and age-related health outcomes and mortality. As a disease closely associated with advancing age,...

    Authors: Ruth A. Sibbett, Drew M. Altschul, Riccardo E. Marioni, Ian J. Deary, John M. Starr and Tom C. Russ

    Citation: BMC Psychiatry 2020 20:91

    Content type: Research article

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  33. Several studies indicate that older age is a risk factor for probable post-traumatic stress disorder (PTSD). However, evidence on the prevalence and risk factors for elderly disaster survivors is limited.

    Authors: Lan Li, Jan D. Reinhardt, Craig Van Dyke, Heng Wang, Maoqiong Liu, Aiko Yamamoto, Qian Chen and Xiuying Hu

    Citation: BMC Psychiatry 2020 20:78

    Content type: Research article

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  34. People with intellectual disability (ID) face considerable barriers to accessing psychiatric health care, thus there is a risk for health disparity. The aims of the present study were 1) to compare specialist ...

    Authors: G. Ahlström, A. Axmon, M. Sandberg and J. Hultqvist

    Citation: BMC Psychiatry 2020 20:70

    Content type: Research article

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  35. The elderly population is rising globally, especially in China where a large population base causes the largest number of older adults in the world. Notably, Shidu people who are over the age of 60 and have lo...

    Authors: Qianlan Yin, Huaihui Zhang, Zhilei Shang, Lili Wu, Zhuoer Sun, Fan Zhang, Yaoguang Zhou, Xiangrui Song and Weizhi Liu

    Citation: BMC Psychiatry 2020 20:37

    Content type: Research article

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  36. Depression comprises common psychological problems, and has been strongly related to neuroticism and perceived stress. While neuroticism has been shown to have a direct effect on depression, it also has an ind...

    Authors: Mukda Banjongrewadee, Nahathai Wongpakaran, Tinakon Wongpakaran, Tanyong Pipanmekaporn, Yodying Punjasawadwong and Sirirat Mueankwan

    Citation: BMC Psychiatry 2020 20:25

    Content type: Research article

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  37. The aim of the current study is to assess the cross-sectional association of chronic non-communicable diseases (hypertension, diabetes mellitus, arthritis, and cerebrovascular) with depressive symptoms among o...

    Authors: Zhenjie Wang, Hanmo Yang, Zhanyuan Guo, Bei Liu and Shen Geng

    Citation: BMC Psychiatry 2019 19:310

    Content type: Research article

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  38. Psychotropic drugs are often prescribed to treat neuropsychiatric symptoms in nursing home residents with dementia, despite having limited efficacy and considerable side effects. To reduce the inappropriate pr...

    Authors: Claudia M. Groot Kormelinck, Charlotte F. van Teunenbroek, Boudewijn J. Kollen, Margreet Reitsma, Debby L. Gerritsen, Martin Smalbrugge and Sytse U. Zuidema

    Citation: BMC Psychiatry 2019 19:298

    Content type: Study protocol

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  40. Intracranial arachnoid cysts are usually benign congenital findings of neuroimaging modalities, sometimes however, leading to focal neurological and psychiatric comorbidities. Whether primarily clinically sile...

    Authors: Anna-Sophia Wahl, Martin Löffler, Lucrezia Hausner, Michaela Ruttorf, Frauke Nees and Lutz Frölich

    Citation: BMC Psychiatry 2019 19:274

    Content type: Case report

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  41. The increasing elderly population worldwide is likely to increase mental health problems such as geriatric depression, which has mostly been studied in high-income countries. Similar studies are scarce in low-...

    Authors: Kedar Manandhar, Ajay Risal, Oshin Shrestha, Nirmala Manandhar, Dipak Kunwar, Rajendra Koju and Are Holen

    Citation: BMC Psychiatry 2019 19:271

    Content type: Research article

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  43. Affective disorders, encompassing depressive-, anxiety-, and somatic symptom disorders, are the most prevalent mental disorders in later life. Treatment protocols and guidelines largely rely on evidence from R...

    Authors: Richard C. Oude Voshaar, Ton D. F. Dhondt, Mario Fluiter, Paul Naarding, Sanne Wassink, Maureen M. J. Smeets, Loeki P. R. M. Pelzers, Astrid Lugtenburg, Martine Veenstra, Radboud M. Marijnissen, Gert-Jan Hendriks, Lia A. Verlinde, Robert A. Schoevers and Rob H. S. van den Brink

    Citation: BMC Psychiatry 2019 19:182

    Content type: Study protocol

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  44. Little is known regarding the burden of comorbidities among older people with intellectual disability (ID) who have affective and anxiety disorders. Therefore, we aimed to investigate the occurrence and risk o...

    Authors: Nadia El Mrayyan, Jonas Eberhard and Gerd Ahlström

    Citation: BMC Psychiatry 2019 19:166

    Content type: Research article

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  45. Amyloid β (Aβ) and tau proteins are considered as critical factors that affect Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Although many studies have conducted on these two proteins, little s...

    Authors: Yuan Li, Zhijun Yao, Yue Yu, Ying Zou, Yu Fu and Bin Hu

    Citation: BMC Psychiatry 2019 19:165

    Content type: Research article

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  46. Depression is common among chronic heart failure (CHF) patients, and it is associated with significant re-hospitalization and mortality as well as lower quality of life. While psychotherapy is efficacious trea...

    Authors: Ying Zhang, Xiaozhen Lv, Wei Jiang, Yun Zhu, Weixian Xu, Yongdong Hu, Wanxin Ma, Peiyun Sun, Qingling Yang, Yulan Liang, Feng Ren, Xin Yu and Huali Wang

    Citation: BMC Psychiatry 2019 19:161

    Content type: Study protocol

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  47. The number of dementia cases is expected to rise exponentially over the years in many parts of the world. Collaborative healthcare partnerships are envisaged as a solution to this problem. Primary care physici...

    Authors: Shan Hui Lai, Tung Tsoi, Chao Tian Tang, Richard Jor Yeong Hui, Kim Kiat Tan, Yehudi Wee Shung Yeo and Ee Heok Kua

    Citation: BMC Psychiatry 2019 19:61

    Content type: Research article

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  48. Dog-assisted therapy (DAT) is a non-pharmacological intervention based on the interaction between patients and dogs, which has been proposed to help adults with dementia. However, evidence to support it is lac...

    Authors: Jessica Hanae Zafra-Tanaka, Kevin Pacheco-Barrios, Walter Andree Tellez and Alvaro Taype-Rondan

    Citation: BMC Psychiatry 2019 19:41

    Content type: Research article

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  49. Several types of psychotherapy have been proven successful in the treatment of personality disorders in younger age groups, however studies among older patients are lacking. We developed a group schema-focused...

    Authors: S. D. M. van Dijk, M. S. Veenstra, R. Bouman, J. Peekel, D. H. Veenstra, P. J. van Dalen, A. D. I. van Asselt, M. L. Boshuisen, S. P. J. van Alphen, R. H. S. van den Brink and R. C. Oude Voshaar

    Citation: BMC Psychiatry 2019 19:26

    Content type: Study protocol

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