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Fig. 3 | BMC Psychiatry

Fig. 3

From: Alterations of monoamine neurotransmitters, HPA-axis hormones, and inflammation cytokines in reserpine-induced hyperalgesia and depression comorbidity rat model

Fig. 3

Reserpine-induced depressive behaviors and hyperalgesia. A The model group showed decreased sucrose preference. B The model group showed decreased horizontal movement distance in the OFT. C The model group showed longer immobility time in the FST. D The model group showed decreased PWT in the von Frey test. E The model group showed decreased thermal threshold in the Hargreaves test. Data is expressed as the mean ± SD. ***p < 0.005, ****p < 0.0001, compared with their respective control group

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