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Table 3 Comparison of frequent primary diagnoses in claims records with prescribed antibiotics

From: Association between depression and antibiotic use: analysis of population-based National Health Insurance claims data

Rank

Patients with MDD (n = 16,950)

PS-matched patients without MDDa

(n = 67,800)

Description (ICD-10 codes)

% of patients

Median Rx days (Q1, Q3)

Median drug costs (Q1, Q3), (US dollar)

Description (ICD-10 codes)

% of patients

Median Rx days (Q1, Q3)

Median drug costs (Q1, Q3), (US dollar)

1

Other acute lower respiratory infections (J20-J22)

26.19

6 (3, 10)***

5.48 (3.28, 10.60)***

Other acute lower respiratory infections (J20-J22)

24.67

5 (3, 8)

4.78 (3.03, 8.83)

2

Diseases of oral cavity and salivary glands (K00-K14)

24.93

5 (3, 8)

2.65 (1.18, 5.48)*

Diseases of oral cavity and salivary glands (K00-K14)

23.85

5 (3, 8)

2.65 (0.95, 5.30)

3

Acute upper respiratory infections (J00-J06)

22.25

5 (3, 9)***

4.78 (2.87, 9.08)***

Acute upper respiratory infections (J00-J06)

20.26

4 (3, 8)

4.36 (2.68, 8.24)

4

Other diseases of the upper respiratory tract (J30-J39)

15.53

6 (3, 11)***

5.72 (3.18, 11.53)**

Other diseases of the upper respiratory tract (J30-J39)

13.54

5 (3, 9)

5.04 (3.09, 10.1)

5

Other diseases of the urinary system (N30-N39)

11.37

7 (4, 14)***

6.43 (3.29, 13.54)***

Chronic lower respiratory diseases (J40-J47)

7.85

5 (3, 9)

5.48(3.28, 10.18)

6

Chronic lower respiratory diseases (J40-J47)

9.47

6 (3, 12)***

6.57 (3.48, 14.2)***

Disorders of eyelid, lacrimal system and orbit (H00-H05)

7.79

3 (1, 5)

5.25 (2.80, 8.41)

7

Infections of the skin and subcutaneous tissue (L00-L08)

8.83

5 (3, 9)

4.26 (2.29, 8.24)

Disorders of conjunctiva (H10-H11)

7.70

1 (1, 3)

3.05 (2.46, 5.64)

8

Disorders of eyelid, lacrimal system and orbit (H00-H05)

8.59

3 (1, 5)*

4.68 (2.80, 8.22)*

Other diseases of the urinary system (N30-N39)

7.54

7 (4, 12)

5.73 (3.18, 11.28)

9

Inflammatory diseases of female pelvic organs (N70-N77)

8.48

6 (3, 11)***

3.04 (0.94, 6.82)***

Infections of the skin and subcutaneous tissue (L00-L08)

7.44

5 (3, 8)

4.26 (2.63, 7.81)

10

Disorders of conjunctiva (H10-H11)

8.33

1 (1, 3)

3.37 (2.59, 5.98)

Inflammatory diseases of female pelvic organs (N70-N77)

6.07

5 (2, 9)

2.29 (0.48, 5.67)

  1. For each diagnosis, a Wilcoxon rank sum test was performed to compare the MDD patients with those without MDD
  2. 1 US dollar equals approximately 1200 Korean won
  3. *p < 0.05; **p < 0.001; ***p < 0.0001
  4. aPatients without MDD were matched with patients with MDD by propensity score based on demographic characteristics, i.e., age, sex, and the type of National Health Security program enrolled
  5. ICD International Classification of Diseases, MDD major depressive disorder, PS propensity score, Q1 25th percentile, Q3 75th percentile, Rx prescription
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BMC Psychiatry

ISSN: 1471-244X

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