Table 7 Neuropsychiatric Inventory - Nursing Home Version (transformed scores) predicted by week, condition, dementia severity and baseline total using multilevel regression
Predictors | Total | Affective symptoms | Psychosis | Agitation | ||||
|---|---|---|---|---|---|---|---|---|
Estimates (CI) | Std. betas (SD) | Estimates (CI) | Std. betas (SD) | Estimates (CI) | Std. betas (SD) | Estimates (CI) | Std. betas (SD) | |
Week (8) | 0.4 (− 0.3–1.0) | 0.2 (1.0) | −0.1 (− 0.5–0.4) | −0.1 (− 0.3) | −0.1 (− 0.6–0.3) | −0.1 (− 0.7) | 0.4 (− 0.1–0.9) | 0.2 (1.6) |
Week (16) | −0.0 (− 0.8–0.7) | −0.0 (− 0.1) | 0.2 (− 0.3–0.7) | 0.1 (0.8) | −0.1 (− 0.6–0.4) | −0.1 (− 0.4) | −0.5 (− 1.0–0.1) | −0.3 (− 1.7) |
Week (24) | −0.4 (− 1.1–0.4) | −0.2 (− 1.0) | −0.4 (− 0.9–0.1) | −0.3 (− 1.6) | 0.0 (− 0.5–0.5) | 0.0 (0.1) | −0.1 (− 0.7–0.4) | −0.1 (− 0.5) |
Condition [Intervention] | 0.3 (− 0.4–1.1) | 0.2 (0.9) | 0.2 (− 0.3–0.7) | 0.1 (0.8) | 0.2 (−0.3–0.7) | 0.1 (0.8) | −0.0 (− 0.5–0.5) | −0.0 (− 0.0) |
Interactions (indicating treatment effect) | Â | |||||||
 Week (8) * [Intervention] | − 0.8 (− 1.8–0.1) | − 0.4 (− 1.7) | − 0.4 (− 1.1–0.2) | −0.3 (− 1.3) | −0.2 (− 0.8–0.4) | −0.1 (− 0.5) | −0.3 (− 1.0–0.4) | −0.2 (− 0.8) |
 Week (16) * [Intervention] | −1.1 *(− 2.2 – − 0.1) | −0.5 (− 2.2) | −0.9 **(− 1.6 – − 0.2) | −0.7 (− 2.6) | −0.5 (− 1.2–0.1) | −0.4 (− 1.5) | 0.2 (− 0.6–0.9) | 0.1 (0.5) |
 Week (24) * [Intervention] | −0.1 (− 1.1–1.0) | −0.0 (− 0.1) | 0.2 (− 0.5–0.9) | 0.2 (0.6) | −0.2 (− 0.9–0.4) | −0.2 (− 0.7) | 0.2 (− 0.6–0.9) | 0.1 (0.5) |
Covariates | Â | |||||||
 FAST | − 0.3 (− 0.7–0.1) | − 0.1 (− 1.6) | 0.0 (−0.2–0.3) | 0.0 (0.4) | −0.1 (− 0.3–0.1) | −0.0 (− 0.8) | −0.2 (− 0.5–0.1) | −0.1 (− 1.6) |
 Baseline DV | 0.7 ***(0.6–0.8) | 0.7 (11.8) | 0.6 ***(0.5–0.7) | 0.7 (12.0) | 0.6 ***(0.5–0.7) | 0.7 (10.8) | 0.7 ***(0.6–0.9) | 0.8 (14.3) |
Model information | Â | |||||||
 ICC | 0.24 | 0.56 | 0.60 | 0.70 | ||||
 Marginal R2 / Conditional R2 | 0.516 / 0.630 | 0.037 / 0.580 | 0.019 / 0.610 | 0.013 / 0.701 | ||||