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Table 2 Clinical variables and psychopharmacological treatment in OCD patients, with or without MDD comorbidity

From: Sleep disturbances in obsessive-compulsive disorder: influence of depression symptoms and trait anxiety

 

OCD without MDD

(N = 35)

OCD with MDD

(N = 26)

Statistic

df

P value

Clinical Variables

 HAM-D-17

6.67 (4.22)

10.04 (5.87)

t = −2.62

59

0.01*

 Y-BOCS

22.55 (6.06)

22.13 (4.46)

t = 0.29

59

0.77

 STAI-Trait

35.11 (9.82)

34.7 (13.50)

t = 0.14

59

0.89

 STAI-State

26.40 (14.40)

26.04 (16.11)

t = 0.09

59

0.93

Psychopharmacological Treatment Doses (DDD)

 SSRI

3 (1.80)

3.12 (2.44)

t = −0.21

59

0.83

 Dual-action antidepressants

0.09 (0.35)

0.38 (0.91)

t = −1.72

59

0.09

 TCA

0.66 (0.91)

0.65(0.90)

t = 0.07

59

0.95

 Other antidepressants

0.01 (0.08)

0.04 (0.20)

t = −0.65

59

0.52

 Benzodiazepines (diazepam equivalents mg/day)

3.47 (6.75)

8.44 (9.35)

t = −2.41

59

0.02*

 Antipsychotics (chlorpromazine equivalents mg/day)

64.86 (116.22)

52.31 (109.70)

t = 0.43

59

0.67

  1. Data are mean (SD). Abbreviations: OCD Obsessive-Compulsive Disorder, MDD Major Depressive Disorder, HAM-D Hamilton Depression Rating Scale, Y-BOCS Yale-Brown Obsessive Compulsive Scale, STAI State-Trait Anxiety Inventory, DDD defined daily doses, SSRI selective serotonin reuptake inhibitors, TCA tricyclic antidepressants
  2. *P < 0.05