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Table 1 Characteristics of patients with treatment resistant depression (TRD) vs matched comparatorsa with treatment for depression

From: Risk and risk factors for disability pension among patients with treatment resistant depression– a matched cohort study

 

TRD N = 3204

Comparators N = 3204

p

n (%)

Men

1363 (42.5)

1363 (42.5)

matched

Women

1841 (57.5)

1841 (57.5)

 

Age (years)b

 18–29

1245 (38.9)

1251 (39.0)

matched

 30–49

1333 (41.6)

1328 (41.5)

 

 50–69

626 (19.5)

625 (19.5)

 

Type of living area

  

matched

 Small municipality

842 (26.3)

842 (26.3)

 

 Medium-sized municipality

1109 (34.6)

1109 (34.6)

 

 Large city

1253 (39.1)

1253 (39.1)

 

Attained education levelb

  

0.0017

  ≤ 9 years

969 (30.2)

842 (26.3)

 

 10–12 years

1442 (45.0)

1504 (46.9)

 

  ≥ 13 years

793 (24.8)

858 (26.8)

 

Family situationb

  

0.0942

 Married, living without children

296 (9.2)

310 (9.7)

 

 Married, living with children

768 (24.0)

695 (21.7)

 

 Unmarried, living without children

1419 (44.3)

1508 (47.1)

 

 Unmarried, living with children

327 (10.2)

299 (9.3)

 

  ≤ 20 years, living with parent/−s

394 (12.3)

392 (12.2)

 

Country of birth

  

< 0.0001

 Sweden

2420 (75.5)

2647 (82.6)

 

 Other European country

165 (5.2)

123 (3.8)

 

 Other than Europe

619 (19.3)

434 (13.6)

 

Long-term sickness absencec

429 (13.4)

418 (13.1)

0.6849

Unemploymentd

  

0.2803

 1–179 days

643 (20.1)

620 (19.4)

 

  ≥ 180 days

185 (5.8)

161 (5.0)

 

History of depression diagnosis

536 (16.7)

536 (16.7)

matched

History of anxiety disordere

621 (19.4)

638 (19.9)

0.5930

History of personality disordere

97 (3.0)

87(2.7)

0.4544

History of substance use disordere

  

0.0425

 None

2895 (90.4)

2847 (88.9)

 

 Alcohol only

143 (4.5)

187 (5.8)

 

 Other/mixed

166 (5.2)

170 (5.3)

 

History of other psychiatric disordere

190 (5.9)

195 (6.1)

0.7927

History of self harm/suicide attempte

208 (6.5)

277 (7.1)

0.3454

CCIe, f

  

0.7685

 0

3029 (94.5)

3016 (94.1)

 

 1

143 (4.5)

155 (4.8)

 

  ≥ 2

32 (1.0)

32 (1.0)

 
  1. aComparators matched on age, sex, calendar year of the index prescription, history of depression, and size of living area
  2. bAt time of first antidepressant prescription
  3. c > 90 net days in the 365 days preceding first antidepressant prescription
  4. dIn the year preceding first antidepressant prescription
  5. eWithin 5 years before first antidepressant prescription
  6. fCharlson’s comorbidity index [40]