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Table 5 Peripheral levels of uric acid, albumin, total bilirubin, and PANSS total scores in schizophrenia before and after treatment

From: Peripheral non-enzymatic antioxidants in patients with schizophrenia: a case-control study

Group

Before

After

t1/t2/t3/t4

P1/P2/P3/P4

UA (μmol/L)

ALB (g/L)

TBIL (μmol/L)

PANSS

UA (μmol/L)

ALB (g/L)

TBIL (μmol/L)

PANSS

SCZ (n = 77)

305.47 ± 78.18

42.61 ± 3.67

17.92 ± 7.32

93.91 ± 17.53

318.00 ± 85.24

39.99 ± 2.23

13.33 ± 5.14

45.19 ± 8.57

1.551/23.300/6.405/5.696

0.125/<0.001/<0.001/<0.001

 Male (n = 27)

348.81 ± 64.89

43.65 ± 3.34

17.75 ± 5.49

90.00 ± 18.82

374.00 ± 77.57

41.03 ± 1.77

14.66 ± 6.02

46.07 ± 9.68

1.791/11.931/3.740/2.266

0.085/0.001/0.032/<0.001

 Female (n = 50)

282.06 ± 75.17

42.04 ± 3.74

18.01 ± 8.20

96.02 ± 16.61

287.76 ± 73.59

39.43 ± 2.26

12.61 ± 4.50

44.72 ± 7.97

0.580/5.148/5.456/20.657

0.564/<0.001/<0.001/<0.001

AU (n = 36)

328.69 ± 78.78

43.29 ± 3.31

16.40 ± 5.74

99.03 ± 20.88

329.53 ± 95.18

40.15 ± 2.16

12.84 ± 3.84

46.28 ± 8.42

0.063/5.807/3.985/14.668

0.950/<0.001/<0.001/<0.001

 Male (n = 15)

359.60 ± 63.40

44.25 ± 2.89

16.99 ± 3.88

93.27 ± 23.26

381.93 ± 83.73

40.79 ± 1.23

14.35 ± 4.04

46.87 ± 8.55

1.220/4.618/1.728/8.126

0.242/<0.001/0.106/<0.001

 Female (n = 21)

306.62 ± 82.58

42.60 ± 3.48

15.98 ± 6.83

103.14 ± 18.49

292.10 ± 86.11

39.69 ± 2.56

11.76 ± 3.37

45.86 ± 8.51

0.801/3.791/3.888/12.802

0.433/0.001/0.001/<0.001

ANF (n = 41)

285.07 ± 72.60

42.00 ± 3.89

19.25 ± 8.32

89.41 ± 12.58

307.88 ± 75.19

39.86 ± 2.30

12.84 ± 6.08

44.24 ± 8.68

2.366/3.592/4.262/20.221

0.023/0.001/<0.001/<0.001

 Male (n = 12)

335.33 ± 66.93

42.90 ± 3.83

19.25 ± 8.32

85.92 ± 10.79

364.08 ± 71.46

41.33 ± 2.31

12.84 ± 6.08

45.08 ± 11.24

1.264/1.269/1.476/9.456

0.232/0.231/0.168/<0.001

 Female (n = 29)

264.28 ± 65.10

41.63 ± 3.92

19.47 ± 8.88

90.86 ± 13.15

284.62 ± 64.48

39.25 ± 2.04

13.23 ± 5.14

43.90 ± 7.59

2.007/3.500/4.136/18.207

0.055/0.002/<0.001/<0.001

  1. AU antipsychotics-use, ANF antipsychotics-naïve/free, UA uric acid, ALB albumin, TBIL total bilirubin, PANSS Positive and Negative Syndrome Scale
  2. t1/t2/t3/t4 and P1/P2/P3/P4 are respectively the statistic of UA, ALB, TBIL, and PANSS