| Anxiety Disorders | Major Depressive Disorder | Substance Use Disorder (Except Cannabis) | ||||||
---|---|---|---|---|---|---|---|---|---|
No (N = 57) | Yes (N = 43) | P-value | No (N = 67) | Yes (N = 33) | P-value | No (N = 48) | Yes (N = 22) | P-value | |
Male (%) | 40 (70.2) | 28 (65.1) | 0.591 | 52 (77.6) | 16 (48.5) | 0.003 | 31 (64.6) | 14 (63.6) | 0.939 |
Current Age (± SD) | 33.9 (± 12.3) | 33.2 (± 13.9) | 0.502 | 34.2 (± 13.6) | 32.4 (± 12.1) | 0.536 | 37.6 (± 13.7) | 28.1 (± 10.3) | 0.003 |
Current Smoker (%) | 11 (19.3) | 10 (23.3) | 0.628 | 16 (23.9) | 5 (15.2) | 0.465 | 6 (12.5) | 8 (36.4) | 0.095 |
Scale Tests (±SD) | |||||||||
 Perceived Stress Scale | 13.7 (± 5.1) | 19.2 (± 6.7) | 0.000 | 14.8 (± 6.1) | 18.6 (± 6.4) | 0.006 | 14.2 (± 6.3) | 19.2 (± 5.8) | 0.002 |
 PROMIS Fatigue | 48.7 (± 7.7) | 54.3 (± 6.6) | 0.000 | 50.0 (± 7.8) | 53.4 (± 6.9) | 0.036 | 51.5 (± 8.4) | 52.3 ± (4.9) | 0.610 |
 PROMIS Sleep Disturbance | 46.0 (± 8.0) | 54.3 (± 6.6) | 0.386 | 46.7 (± 8.6) | 46.3 (± 8.5) | 0.831 | 47.8 (± 8.8) | 47.4 (± 7.9) | 0.851 |
 Beck Depression | 4.1 (± 3.4) | 12.3 (± 7.6) | 0.000 | 6.3 (± 5.8) | 10.3 (± 8.3) | 0.017 | 5.9 (± 5.3) | 10.8 (± 7.5) | 0.002 |
 Patient Health Questionnaire | 4.6 (± 3.2) | 8.5 (± 4.4) | 0.000 | 5.5 (± 3.8) | 7.8 (± 4.6) | 0.009 | 6.1 (± 3.9) | 7.4 (± 3.7) | 0.174 |
 BPI Pain Rating | 13.8 (± 9.2) | 15.3 (± 11.0) | 0.686 | 11.8 (± 8.6) | 18.2 (± 11.3) | 0.068 | 14.1 (± 9.5) | 13.2 (± 11.6) | 0.857 |
 BPI Pain Interference | 16.6 (± 13.8) | 14.8 (± 11.8) | 0.696 | 13.1 (± 11.8) | 18.2 (± 12.8) | 0.231 | 16.3 (± 13.4) | 13.5 (± 15.0) | 0.685 |
 Fagerstrom | 2.7 (± 2.0) | 2.9 (± 2.6) | 0.866 | 2.9 (± 1.9) | 2.4 (± 3.4) | 0.748 | 1.5 (± 1.6) | 3.5 (± 1.9) | 0.058 |
 Age of First Cannabis Use (± SD) | 17.1 (± 3.8) | 17.6 (± 5.8) | 0.783 | 17.5 (± 5.1) | 17.0 (± 4.2) | 0.510 | 17.8 (± 4.7) | 18.1 (± 6.5) | 0.931 |
 Age of Onset of Regular Use (SD) | 20.7 (± 6.3) | 20.0 (± 6.3) | 0.296 | 20.5 (± 6.7) | 20.1 (± 5.3) | 0.807 | 21.7 (± 7.2) | 20.4 (± 6.7) | 0.192 |
Reason for Medicinal Cannabis Use (%) | |||||||||
 Conventional treatments don’t work | 9 (15.8) | 11 (25.6) | 0.226 | 11 (16.4) | 9 (27.3) | 0.202 | 7 (14.6) | 9 (40.9) | 0.015 |
 My doctor recommended it to me | 1 (1.8) | 8 (18.6) | 0.004 | 6 (9.0) | 3 (9.1) | 0.982 | 3 (6.2) | 4 (18.2) | 0.122 |
 Internet search on treatments for my condition | 5 (8.8) | 10 (23.3) | 0.045 | 8 (11.9) | 7 (21.2) | 0.222 | 6 (12.5) | 5 (22.7) | 0.275 |
 Experiences Pain (%) | 12 (21.1) | 23 (53.5) | 0.001 | 19 (28.4) | 16 (48.5) | 0.047 | 14 (29.2) | 6 (27.3) | 0.871 |
Condition (%) | |||||||||
 Anxiety/Stress | 38 (66.7) | 39 (90.7) | 0.005 | 50 (74.6) | 27 (81.8) | 0.422 | 36 (75.0) | 15 (68.2) | 0.552 |
 Depression | 18 (31.6) | 29 (67.4) | 0.000 | 25 (37.3) | 22 (66.7) | 0.006 | 15 (31.2) | 13 (59.1) | 0.027 |
 Insomnia/Sleep Issues | 29 (50.9) | 24 (55.8) | 0.624 | 36 (53.7) | 17 (51.5) | 0.835 | 24 (50.0) | 17 (77.3) | 0.032 |
 Bipolar | 0 (0.0) | 5 (11.6) | 0.008 | 4 (6.0) | 1 (3.0) | 0.526 | 1 (2.1) | 3 (13.6) | 0.053 |
 Dispensary Visits Per Month (± SD) | 4.2 (± 3.5) | 3.9 (± 3.4) | 0.664 | 3.7 (± 3.3) | 4.7 (± 3.7) | 0.151 | 3.1 (± 3.1) | 5.0 (± 3.6) | 0.002 |
 Cannabis Use Quantity, grams per week (± SD) | 4.5 (± 4.8) | 4.0 (± 4.6) | 0.497 | 3.9 (± 3.2) | 5.2 (± 7.0) | 0.911 | 3.4 (± 3.3) | 4.1 (± 2.0) | 0.038 |
 Cannabis Use Frequency, times per month (± SD) | 50.2 (± 27.8) | 42.9 (± 34.3) | 0.185 | 47.7 (± 30.8) | 45.6 (± 31.1) | 0.836 | 39.5 (± 28.7) | 59.3 (± 28.7) | 0.012 |
 Time of Use: On an as-needed basis (%) | 14 (24.6) | 23 (53.5) | 0.003 | 22 (32.8) | 15 (45.5) | 0.219 | 18 (37.5) | 8 (36.4) | 0.927 |
Form of Consumption (%) | |||||||||
 Smoking | 42 (73.7) | 29 (67.4) | 0.496 | 50 (74.6) | 21 (63.6) | 0.255 | 26 (54.2) | 21 (95.5) | 0.001 |
 Vaporizer | 22 (38.6) | 20 (46.5) | 0.427 | 26 (38.8) | 16 (48.5) | 0.356 | 23 (47.9) | 5 (22.7) | 0.046 |
 Tincture | 5 (8.8) | 10 (23.3) | 0.045 | 7 (10.4) | 8 (24.2) | 0.069 | 10 (20.8) | 0 (0.0) | 0.021 |
 Capsules | 6 (10.5) | 11 (25.6) | 0.047 | 6 (9.0) | 11 (33.3) | 0.002 | 8 (16.7) | 1 (4.5) | 0.160 |
 Cannabis Product: CBD Capsules (%) | 5 (8.8) | 18 (41.9) | 0.000 | 11 (16.4) | 12 (36.4) | 0.026 | 9 (18.8) | 4 (18.2) | 0.955 |
 Concentration: Pure CBD (%) | 6 (10.5) | 12 (27.9) | 0.025 | 9 (13.4) | 9 (27.3) | 0.09 | 10 (20.8) | 2 (9.1) | 0.226 |
 Experienced Negative Effects with Cannabis Use (%) | 24 (42.1) | 30 (69.8) | 0.008 | 34 (50.7) | 20 (60.6) | 0.392 | 18 (37.5) | 13 (59.1) | 0.106 |
Negative Effects (%) | |||||||||
 Short-term memory loss | 10 (17.5) | 15 (34.9) | 0.047 | 17 (25.4) | 8 (24.2) | 0.902 | 7 (14.6) | 8 (36.4) | 0.039 |
 Increased anxiety | 16 (28.1) | 20 (46.5) | 0.057 | 24 (35.8) | 12 (36.4) | 0.958 | 12 (25.0) | 11 (50.0) | 0.039 |
 Paranoia | 8 (14.0) | 18 (41.9) | 0.002 | 16 (23.9) | 10 (30.3) | 0.491 | 6 (12.5) | 9 (40.9) | 0.007 |