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Table 1 Patient demographic and clinical characteristics

From: Patient characteristics, burden and pharmacotherapy of treatment-resistant schizophrenia: results from a survey of 204 US psychiatrists

 

TRS

(n = 408)

Non-TRS

(n = 204)

p-value

Age (years), mean (SD)

39.3 (11.3)

36.0 (11.8)

0.001

Distribution, % (n)

  < 18

0.0 (0)

0.5 (1)

0.16

 18–24

6.4 (26)

15.2 (31)

< 0.001

 25–34

32.6 (133)

37.7 (77)

0.21

 35–44

25.2 (103)

25.0 (51)

0.95

 45–54

22.8 (93)

10.3 (21)

< 0.001

 55–64

12.0 (49)

10.3 (21)

0.53

  ≥ 65

1.0 (4)

1.0 (2)

0.50

Male, % (n)

73.0 (298)

64.7 (132)

0.034

Occupational status, % (n)

 Unemployed

74.5 (304)

45.1 (92)

< 0.001

 Employed part-time

8.8 (36)

23.5 (48)

< 0.001

 Employed full-time

5.4 (22)

11.8 (24)

0.005

 In education/studying

4.9 (20)

9.8 (20)

0.021

 Volunteering

4.4 (18)

7.8 (16)

0.081

 Unknown

2.0 (8)

2.0 (4)

0.50

Marital status, % (n)

 Single

71.8 (293)

68.1 (139)

0.35

 Divorced

13.5 (55)

12.3 (25)

0.67

 Married/long-term relationship

10.0 (41)

15.2 (31)

0.063

 Widowed

1.2 (5)

1.5 (3)

0.80

 Unknown

3.4 (14)

2.9 (6)

0.75

Living arrangements, % (n)

 With a partner/family

40.9 (167)

53.4 (109)

0.004

 In a sheltered home

29.4 (120)

10.8 (22)

< 0.001

 Alone

20.1 (82)

26.0 (53)

0.099

 With friends

5.4 (22)

5.9 (12)

0.80

 No fixed address

2.9 (12)

1.5 (3)

0.27

 Unknown

1.2 (5)

2.5 (5)

0.26

Age at symptom onset (years), mean (SD)

22.4 (6.0)

22.8 (5.9)

0.49

Age at diagnosis (years), mean (SD)

24.1 (5.8)

24.7 (6.5)

0.31

Time between symptom onset and diagnosis (years), mean (SD)

1.8 (2.3)

1.8 (3.0)

0.76

Hospitalization status, % (n)

 At least twice (but not currently)

72.5 (296)

39.7 (81)

< 0.001

 Once only (but not currently)

13.2 (54)

31.4 (64)

< 0.001

 Currently hospitalized (also in past)

6.4 (26)

2.5 (5)

0.038

 Currently hospitalized (first time)

1.2 (5)

0.5 (1)

0.39

 Never

4.9 (20)

23.5 (48)

< 0.001

 Unknown

1.7 (7)

2.5 (5)

0.54

Number of hospitalizations (for patients with > 1 hospitalization), mean (SD)

(n = 322)

(n = 86)

 

7.2 (7.0)

5.7 (4.2)

0.090

Number of suicide attempts, mean (SD)

0.9 (1.5)

0.5 (1.3)

0.004

Distribution, % (n)

 0

50.0 (204)

69.1 (141)

< 0.001

 1

15.4 (63)

9.3 (19)

0.036

 2

14.0 (57)

3.4 (7)

< 0.001

 3 or more

8.1 (33)

6.4 (13)

–

 Unknown

12.5 (51)

11.8 (24)

0.79

  1. SD standard deviation; TRS treatment-resistant schizophrenia
  2. p-values in bold are < 0.05