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Table 2 Type and prevalence of comorbid chronic conditions in the study population with and without AD use

From: Antidepressant prescription practice and related factors in Switzerland: a cross-sectional analysis of health claims data

  Total N (%) With AD use N (%) Without AD use N (%) χ2 (df) P
Chronic conditions
 Acid related disorders 231,616 (19.8) 50,245 (47.6) 181,371 (17.0) 56,306 (1) < 0.001a
 Bone diseases (osteoporosis) 21,143 (1.8) 5007 (4.7) 16,136 (1.5) 5618.5 (1) < 0.001a
 Cancer 15,955 (1.4) 3076 (2.9) 12,879 (1.2) 2064.2 (1) < 0.001a
 Cardiovascular diseases (incl. hypertension) 279,956 (23.9) 52,975 (50.1) 226,981 (21.3) 43,782 (1) < 0.001a
 Dementia 20,062 (1.7) 6808 (6.4) 13,254 (1.2) 15,395 (1) < 0.001a
 Diabetes mellitus 56,381 (4.8) 10,877 (10.3) 45,504 (4.3) 7581.5 (1) < 0.001a
 Epilepsy 33,742 (2.9) 13,474 (12.8) 20,268 (1.9) 40,354 (1) < 0.001a
 Glaucoma 38,163 (3.3) 6719 (6.4) 31,444 (3.0) 3525.2 (1) < 0.001a
 Gout, Hyperuricemia 18,380 (1.6) 2818 (2.7) 15,562 (1.5) 900.13 (1) < 0.001a
 HIV 2365 (0.2) 417 (0.4) 1948 (0.2) 212.07 (1) < 0.001a
 Hyperlipidemia 125,564 (10.7) 23,948 (22.7) 101,616 (9.6) 17,242 (1) < 0.001a
 Intestinal inflammatory diseases 5144 (0.4) 1135 (1.1) 4009 (0.4) 1065.7 (1) < 0.001a
 Iron deficiency anemia 56,746 (4.9) 10,527 (10.0) 46,219 (4.3) 6570.1 (1) < 0.001a
 Migraines 12,958 (1.1) 3252 (3.1) 9706 (0.9) 4110.9 (1) < 0.001a
 Pain 106,865 (9.1) 29,862 (28.3) 77,003 (7.2) 51,163 (1) < 0.001a
 Parkinson’s disease 10,846 (0.9) 4233 (4.0) 6613 (0.6) 11,979 (1) < 0.001a
 Psychoses 35,061 (3.0) 19,466 (18.4) 15,595 (1.5) 95,027 (1) < 0.001a
 Respiratory illness (asthma, COPD) 99,180 (8.5) 16,164 (15.3) 83,016 (7.8) 6954.1 (1) < 0.001a
 Rheumatologic conditions 138,197 (11.8) 29,732 (28.1) 108,465 (10.2) 29,694 (1) < 0.001a
 Thyroid disorders 44,201 (3.8) 10,161 (9.6) 34,040 (3.2) 10,880 (1) < 0.001a
 Tuberculosis 883 (0.1) 169 (0.2) 714 (0.1) 108.55 (1) < 0.001a
  1. CCCs Classification of comorbid chronic conditions is based on medication prescriptions related to the disorder; aChi-square test