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Fig. 1 | BMC Psychiatry

Fig. 1

From: The cytokine profile of women with severe anxiety and depression during pregnancy

Fig. 1

Concentrations of Th1-related cytokines in tested groups. The figure depicts the Log10 concentration values of estimated Th1-related cytokines in serum in the CTRL, SA, and SA + SD groups, respectively. Th1-related cytokines were quantified by flow cytometry (see methods). The concentration values of proinflammatory cytokines are expressed as the mean ± SEM, as described: CTRL; IL-2 (3.5 ± 0.4 pg/mL), IL-6 (3.3 ± 0.4 pg/mL), TNF-α (5.6 ± 0.5 pg/mL), IFN-γ (5.3 ± 0.3 pg/mL). SA; IL-2 (33.7 ± 5.7 pg/mL), IL-6 (33.3 ± 5.9 pg/mL), TNF-α (85.9 ± 1.8 pg/mL), IFN-γ (86.5 ± 2.1 pg/mL). SA + SD; IL-2 (85.8 ± 5.7 pg/mL), IL-6 (83.4 ± 9.2 pg/mL), TNF-α (119.5 ± 6.2 pg/mL), IFN-γ (103.5 ± 5.4 pg/mL). The non-parametric, t-test analysis with Welch’s correction was used to estimate the p-values for each Th2-related cytokine assayed among the studied groups. (*) p ≤ 0.05; (**); p ≤ 0.001; (***) p ≤ 0.0001. Significant differences were established at a p < 0.05. Abbreviations: SA + SD, severe anxiety plus comorbid severe, severe anxiety; CTRL; control. Data were calculated using GraphPad v.7

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