Table 1 Characteristics of studies assessing prevalence of depression among patients with subclinical hypothyroidism
Author, year | Country | Setting | Study type | Depression Scale | SCH pts, n | M:F | Mean age (SD) | Mean TSH mIU/L (SD) | MDD, n | Non SCH Pts, n | M:F | Mean age (SD) | Mean TSH mIU/L (SD) | MDD, n | NOS scores |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Haggerty 1993 | USA | Community | Cross section | HDRS | 16 | 0:16 | 36.3 (9.3) | 4.6 (2.7) | 9 | 15 | 0:15 | 34.2 (10.1) | 1.7 (0.7) | 3 | 8 |
Baldini 1997 | Italy | Outpatient | Prospective | HDRS | 19 | 0:19 | 55.2 (8.8) | 12.0 (7.2) | NA | 17 | 0:17 | 50.2 (9.2) | 1.2 (1.2) | NA | 9 |
Chueire 2002 | Brazil | Outpatient | Cross section | SCI | 112 | NA | NA | NA | 26 | 138 | NA | NA | NA | 16 | 7 |
Aslan 2005 | Turkey | Outpatient | Cross section | HDRS | 7 | NA | 39.2 (10.2) | 93.8 (225) | 1 | 15 | NA | 42.5 (11.0) | 1.6 (1.1) | 4 | 8 |
Gulseren 2006 | Turkey | Outpatient | Prospective | HDRS | 43 | 5:38 | 40.9 (14.2) | 17.6 (2.16) | NA | 20 | NA | 40.5 (7.6) | 2.96 (0.96) | NA | 9 |
Jorde 2006 | Norway | Community | Prospective | BDI | 89 | 45:44 | 62.4 (11.9) | 5.72 (1.68) | NA | 154 | 72:82 | 61.0 (12.5) | 1.79 (0.69) | NA | 9 |
Almeida 2006 | Brazil | Outpatient | Cross section | HDRS | 94 | 5:89 | 49.1 (10.3) | NA | 24 | 43 | 3:40 | 44.8 (9.6) | NA | 7 | 7 |
BDI | 43 | 9 | |||||||||||||
Park 2009 | Korea | Community | Cross section | GDS-K | 164 | 73:91 | 76.5 (9.0) | 6.79 (3.77) | 9 | 754 | 327:427 | 76.8 (9.0) | 2.28 (0.91) | 40 | 8 |
De Jongh 2011 | Netherlands | Community | Cross section | CESD | 64 | 20:44 | 74.9 (6.8) | 6.89 | 11 | 1121 | 569:552 | 75.5 (6.5) | 1.50 | 155 | 8 |
Demartini 2014 | Italy | Outpatient | Cross section | HDRS | 123 | 7:116 | 62.5 (13.4) | 13.5 (14.9) | 78 | 123 | 11:112 | 52.0 (14.7) | 2.7 (1.0) | 34 | 7 |
MADRS | 79 | 36 | |||||||||||||
Silva 2014 | Brazil | Outpatient | Cross section | GDS-15 | 43 | 8:35 | 81.2 (6.7) | 5.5 (1.2) | 30 | 235 | 55:180 | 80.3 (6.8) | 2.1 (0.9) | 107 | 7 |
CSDD | |||||||||||||||
Fjaellegaard 2014 | Denmark | Community | Cross section | WHO-MDI | 580 | 252:328 | 53 | 4.5 | 2 | 7634 | 3696:3938 | 53 | 1.7 | 3 | 8 |
Vishnoi 2014 | India | Outpatient | Prospective | HDRS | 300 | 92:208 | 52.5 (11.5) | 7.8 (1.7) | 185 | 300 | 87:213 | 52.4 (11.5) | 2.8 (1.3) | NA | 9 |
Krysiak 2016 | Poland | Community | Cross section | BDI | 17 | 0:17 | 31 (5) | 7.5 (1.2) | 10 | 16 | 0:16 | 30 (5) | 2.6 (1.0) | 6 | 9 |
Krysiak 2016 | Poland | Community | Cross section | BDI | 17 | 0:17 | 30 (4) | 7.3 (1.3) | 6 | 18 | 0:18 | 29 (4) | 1.7 (0.6) | 3 | 9 |
Krysiak 2017 | Poland | Outpatient | Prospective | BDI | 12 | 12:0 | 35 (6) | 12.3 (4.0) | 5 | 12 | 12:0 | 34 (7) | 1.6 (0.8) | 1 | 10 |