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Table 3 Fatal toxicity indices – number of suicides involving a given drug per individuals prescribed this drug relative to a. lithium or b. chlorpromazine

From: Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning

 

Odds ratio (95% CI)

Single drug only

Single plus first listed drug

A. Mood Stabilisers

 Lithium

1.0

1.0

 Sodium Valproate

0.80 (0.31–2.07)

0.58 (0.27–1.25)

 Carbamazepine

1.45 (0.61–3.45)

1.47 (0.75–2.89)

 Lamotrigine

0.54 (0.17–1.77)

0.78 (0.34–1.80)

B. Antipsychotics

 Chlorpromazine

1.0

1.0

 Risperidone

0.04 (0.01–0.29)

0.05 (0.01–0.21)

 Quetiapine

1.26 (0.66–2.40)

1.29 (0.77–2.15)

 Olanzapine

1.63 (0.87–3.05)

1.46 (0.89–2.41)