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Table 3 NET8 (rs5569), CHRNA4 (rs1044396) and CRHR1 (rs28364027) genotypes and allele frequencies between IGA and non-IGA groups

From: Genetic association of human Corticotropin-Releasing Hormone Receptor 1 (CRHR1) with Internet gaming addiction in Korean male adolescents

Gene (SNP) MAF Genotype IGA (n = 116) Non-IGA (n = 114) χ21 p1 Allele type IGA (n = 116) Non-IGA (n = 114) χ22 p2 OR (95% CI)
  n (%) n (%)   n (%) n (%)
NET8 (rs5569) 0.25 AA 65 (58.6) 70 (50.2) 0.89 .640 A 177 (76.0) 167 (73.2) 0.50 .450 0.78 (0.47–1.32)
  AG 41 (35.3) 47 (41.3)   G 56 (24.0) 61 (26.8)
  GG 7 (6.1) 7 (6.1)
CHRNA4 (rs1044396) 0.21 CC 68 (58.6) 71 (62.3) 0.59 .730 C 180 (77.6) 180 (78.9) 0.10 .730 1.17 (0.63–1.95)
  CT 44 (37.9) 38 (33.3)   T 52 (22.4) 48 (21.1)
  TT 4 (3.5) 5 (4.4)
CRHR1 (rs28364027) 0.07 AA 107 (92.2) 93 (81.6) 5.76 .016 A 223 (97.8) 207 (94.7) 5.36 .021 2.63 (1.17–6.15)
  AG 9 (7.8) 21 (18.4)   G 9 (2.2) 21 (5.3)
  GG 0 (0.0) 0 (0.0)
  1. IGA Internet gaming addiction, non-IGA non-Internet gaming addiction, SNP single nucleotide polymorphism, MAF minor allele frequency; χ21, χ2 in comparison of genotype frequency between IGA and non-IGA; p1, p-value in comparison of genotype frequency between IGA and non-IGA; χ22, χ2 in comparison of allele frequency between IGA and non-IGA; p2, p-value in comparison of allele frequency between IGA and non-IGA; OR, odds ratio; CI, confidence interval