Table 2 Demographics and baseline clinical characteristics of TRD and non-TRD patients
From: Humanistic outcomes in treatment resistant depression: a secondary analysis of the STAR*D study
Variable | N | TRD | N | Non-TRD | P-Value |
|---|---|---|---|---|---|
Age at entry to study; mean years (SD) | 377 | 44.3 (11.97) | 2090 | 41.8 (13.26) | 0.0005 |
Age, years; (%) | 0.0004 | ||||
 18–34 | 98 | 26 | 734 | 35.1 |  |
 35–49 | 145 | 38.5 | 744 | 35.6 |  |
 50–64 | 122 | 32.4 | 512 | 24.5 |  |
 65+ | 12 | 3.2 | 100 | 4.8 |  |
Gender; n (%) | <.0001 | ||||
 Female | 193 | 51.2 | 1322 | 63.2 |  |
 Male | 184 | 48.8 | 769 | 36.8 |  |
HDRS17 current score (transcribed); mean (SD) | 377 | 24.4 (5.10) | 2089 | 22.0 (4.80) | <.0001 |
Depression severity by HDRS17; (%) | <.0001 | ||||
 Mild (score: 8–13) | 0 | 0 | 3 | 0.1 |  |
 Moderate (score:14–19) | 63 | 16.7 | 703 | 33.7 |  |
 Severe (score: 20–25) | 164 | 43.5 | 920 | 44 |  |
 Very severe (score:26+) | 150 | 39.8 | 463 | 22.2 |  |
QIDS-C current score (transcribed); mean (SD) | 377 | 17.5 (3.19) | 2089 | 15.8 (3.27) | <.0001 |
Depression severity by QIDS-SR16; (%) | <.0001 | ||||
 No Depression (score:0–5) | 0 | 0 | 25 | 1.2 |  |
 Mild (score:6–10) | 18 | 4.8 | 308 | 14.8 |  |
 Moderate (score:11–15) | 115 | 30.6 | 861 | 41.3 |  |
 Severe (score:16–20) | 168 | 44.7 | 693 | 33.3 |  |
 Very severe (score:21+) | 75 | 19.9 | 197 | 9.5 |  |
QIDS-SR current score (transcribed); mean (SD) | 376 | 17 (3.86) | 2084 | 14.7 (4.25) | <.0001 |
Total severity score of comorbid condition; mean (SD) | 377 | 5.6 (4.43) | 2091 | 4.3 (3.66) | <.0001 |