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Table 1 STAR*D study design and categorization of patients (TRD vs non-TRD)

From: Humanistic outcomes in treatment resistant depression: a secondary analysis of the STAR*D study

  Non-TRD TRD
Non-TRD 1 Non-TRD 2 TRD1 TRD2
Patients Entered Follow-up after Patients Entered Follow-up after Patients Entered Follow-up after Patients Entered Patients Entered
Level 1 Level 2 Level 2A Level 3 Level 4
Level 1 Baseline X X X X X
Level 2   X X X X
Level 2A    X X X
Level 3     X X
Level 4      X
Follow-up X X X X X
  1. TRD treatment resistant depression
  2. A detailed description of STAR*D study design and different levels of treatment has been presented elsewhere: Rush AJ, Fava M, Wisniewski SR et al. Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design. Control Clin Trials 2004; 25: 119–42