From: Impact of childhood trauma on sensory gating in patients with first-episode schizophrenia
Schizophrenia patients (N = 56) | Controls (N = 49) | X2/t | P | |
---|---|---|---|---|
Gender, M/F | 22/34 | 25/24 | 1.442 | 0.245 |
Age, years | 25.90 ± 6.80 | 26.21 ± 3.90 | − 0.274 | 0.785 |
Education, years | 13.18 ± 3.24 | 14.12 ± 3.27 | −1.372 | 0.173 |
DUP, months | 29.92 ± 29.63 | |||
Drug-naïve/ on medication | 24/32 | |||
Risperidone 10 | ||||
Paliperidone 6 | ||||
Olanzapine 7 | ||||
Aripiprazole 6 | ||||
Quetiapine 3 | ||||
On medication>2w/<2w | 11/21 | |||
PANSS | ||||
Total | 82.28 + 22.32 | |||
Positive | 22.57 ± 7.17 | |||
Negative | 19.25 ± 9.33 | |||
General Psychopathology | 43.02 ± 5.57 | |||
Childhood trauma | ||||
Total | 42.89 ± 11.60 | 38.60 ± 8.86 | 1.919 | 0.058 |
Emotional abuse | 7.97 ± 3.22 | 7.00 ± 2.48 | 1.589 | 0.116 |
Physical abuse | 6.11 ± 2.15 | 6.26 ± 2.08 | − 0.314 | 0.754 |
Sexual abuse | 6.47 ± 2.13 | 5.50 ± 1.06 | 2.729 | 0.008 |
Emotional neglect | 12.83 ± 5.04 | 10.97 ± 3.94 | 1.910 | 0.060 |
Physical neglect | 9.87 ± 3.16 | 8.86 ± 2.31 | 1.679 | 0.097 |
PPI index | ||||
Startle | 77.41 ± 36.82 | 74.73 ± 30.33 | 0.322 | 0.748 |
PPI (ISI = 120 ms), % | ||||
PSC PPI | 20.20 ± 25.86 | 27.77 ± 20.31 | −1.321 | 0.191 |
PSS PPI | 21.06 ± 23.13 | 37.82 ± 20.58 | −3.089 | 0.003 |
PPI (ISI = 60 ms), % | ||||
PSC PPI | 19.98 ± 19.60 | 28.45 ± 18.57 | −1.748 | 0.086 |
PSS PPI | 21.03 ± 17.66 | 41.07 ± 19.56 | −4.196 | 0.000 |