Table 1 Demographic, clinical and medication information of bipolar patients and healthy controls
From: Differential mitochondrial DNA copy number in three mood states of bipolar disorder
| Â | Bipolar patients | Health control | Statistic | ||||
|---|---|---|---|---|---|---|---|
Manic N = 55 | Depression N = 47 | Euthymic N = 29 | N = 34 |  | |||
Age, mean (SD) | 26.67 (7.15) | 26.94 (8.91) | 23.76 (3.94) | 24.50 (3.82) | ANOVA, F = 2.05, P = 0.108 | ||
Sex | |||||||
 Male | 26 | 23 | 9 | 19 |  | ||
 Female | 23 | 24 | 20 | 15 | df = 3, X2 = 4.13, P = 0.25 | ||
Years of education, mean (SD) | 12.55 (2.80) | 12.38 (3.47) | 12.24 (2.52) | 13.56 (2.78) | ANOVA, F = 1.41, P = 0.13 | ||
 BMI, mean(SD) | 21.63 (1.89) | 21.45 (1.78) | 21.93 (1.69) | 21.5 (1.40) | ANOVA, F = 1.63, P = 0.18 | ||
Medication information | Â | ||||||
 Antipsychotics | 51/55 | 37/47 | 23/29 |  | df = 2, X2 = 4.69, P = 0.09 | ||
Anticonvulsants | 24/55 | 21/47 | 18/29 |  | df = 2, X2 = 2.92, P = 0.23 | ||
 CPZ equivalents, mean(SD) | 241.58 (93.43) | 224.55 (79.90) | 227.31 (64.16) |  | ANOVA, F = 0.519, P = 0.67 | ||
Benzodiazepines | 15/55 | 17/47 | 5/29 |  | df = 2, X2 = 3.22, P = 0.20 | ||
 Lithium | 22/55 | 19/47 | 12/29 |  | df = 2, X2 = 4.72, P = 0.094 | ||
Clinical characteristics | Man vs Eut | Dep vs Eut | Man vs Dep | ||||
 Duration of illness, months, mean (SD) | 70.91(59.24) | 67.70 (61.91) | 47.45 (34.66) |  | P = 0.140 | P = 0.361 | P = 1 |
YMRS, mean(SD) | 33.78 (6.08) | 8.19 (7.31) | 2.78 (2.24) |  | P < 0.001 | P < 0.001 | P < 0.001 |
 HDRS, mean(SD) | 6.90 (8.24) | 27.89 (6.61) | 2.63 (3.18) |  | P < 0.001 | P < 0.001 | P < 0.001 |
Number of Previous Episodes, mean (SD) | 3.55 (1.74) | 3.60 (1.70) | 2.90 (2.28) |  | P = 0.713 | P = 0.654 | P = 1 |
 MtDNAcn, Median (range) | 1.59 (1.31,2.07) | 1.83 (1.22,2.31) | 2.05 (1.5,2.96) | 2.38 (1.77,3.24) |  |  |  |