Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study

Table 3 Logistic regression showing odd ratios associated with TRD-UP instead of BP disorder (N = 194)

Variables	Coefficient B	SEM	Wald	P value	OR Exp(B)	OR 95% CI
Variables	Coefficient B	SEM	Wald	P value	OR Exp(B)	Lower	Upper
Individual characteristics
Age of 1st depression	−0.051	0.025	4.003	0.045	0.951	0.905	0.999
Marital status	1.583	0.701	5.108	0.024	4.872	1.234	19.235
First degree relatives with affective disorders	0.262	0.593	0.195	0.659	1.299	0.406	4.157
More than one hospitalization for depression	−2.148	0.614	12.239	0.001	0.177	0.035	0.389
Psychotherapy treatment	−2.232	0.699	10.190	0.001	0.107	0.027	0.423
History of suicide attempt	−0.135	0.625	0.047	0.829	0.874	0.257	2.974
Comorbidities
Current anxiety disorders	2.357	0.608	15.033	0.001	10.560	3.208	34.763
Severity of depression
Melancholic depressive features	0.650	0.747	0.755	0.385	1.915	0.422	8.285
Failed pharmacotherapies	0.266	0.106	6.331	0.012	1.304	1.060	1.604
HAM-D17 score	−0.193	0.067	8.208	0.004	0.824	0.722	0.941
Level of functioning
Global assessment of functioning score (GAF)	0.164	0.047	11.985	0.001	1.178	1.074	1.293

TRD-UP Treatment-Resistant Unipolar Depression, BP Bipolar disorder type I and type II, OR Odds ratio, CI Confidence interval, SEM Standard Error of Mean. Boldface indicates significant association at an alpha level = 0.01

ISSN: 1471-244X