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Table 2 Severity of depression and global functioning of patients with TRD-UP and BP. Data are reported as Mean ± SD

From: Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study

Depression severity

TRD-UP (n = 100)

BP (n = 94)

Statistics

MADRS

30.8 ± 8.95

23.2 ± 6.98

t = 6.66, p < 0.001

HAMD-17

23.2 ± 6.24

17.0 ± 4.61

t = 7.92, p < 0.001

QIDS

15.8 ± 4.26

12.7 ± 3.91

t = 5.31, p < 0.001

CGI-S

5.0 ± 1.21

4.3 ± 1.18

t = 4.19, p < 0.001

GAF

55.5 ± 10.22

60.9 ± 4.66

t = −4.93, p < 0.001

  1. TRD-UP Treatment-Resistant Unipolar Depression, BP Bipolar disorder type I and type II, MADRS Montgomery–Asberg Depression Rating Scale, CGI-S Clinical Global Impression-Severity of Illness, QIDS Quick Inventory of Depressive Symptomatology, HAM-D17 Hamilton-Rating Scale for Depression, GAF Global Assessment of functioning, SD Standard Deviation. Boldface indicates significant difference at an alpha level = 0.05