From: Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression
Characteristic | No depression n = 288 | MDD and/or CES-D ≥ 16 n = 92 | Difference p-valuea |
---|---|---|---|
 | Mean ± SD |  | |
Age | 71.6 ± 4.5 | 71.6 ± 4.2 | 0.987 |
 | % |  | |
Female | 52.4 | 78.3 | < 0.001 |
Higher (≥12 years) education level | 39.6 | 25.0 | 0.011 |
Living alone | 18.4 | 38.0 | < 0.001 |
Regular alcohol consumption (>24Â g/day) | 22.6 | 15.2 | 0.141 |
Current smoking (>10 pack years) | 37.5 | 32.6 | 0.421 |
Functional impairmentb | 1.4 | 4.3 | 0.085 |
Cognitive impairmentc | 3.5 | 14.1 | < 0.001 |
Cardiovascular diseased | 12.5 | 7.6 | 0.197 |
Other reported health conditions or related treatmentse | 13.9 | 8.7 | 0.192 |
Obese (BMI ≥ 30) | 6.3 | 10.9 | 0.140 |
Antidepressant usef | 1.7 | 10.9 | < 0.001 |