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Table 1 Selected Baseline Characteristics by Treatment Status at Enrollment, REACH-OUT (2010–2013)

From: Comparison and predictors of treatment adherence and remission among patients with schizophrenia treated with paliperidone palmitate or atypical oral antipsychotics in community behavioral health organizations

Variable

PP-All N = 482

PP-C N = 308

PP-N N = 174

OAT N = 281

P Value, PP-All vs OAT

P Value, PP-N vs OAT

Age (Mean ± SD)

41.12 ± 12.6

42.0 ± 12.7

39.6 ± 12.2

42.1 ± 13.4

0.440

0.069

Male

344 (71%)

219 (72%)

125 (74%)

181 (66%)

0.046

0.074

Race

    

0.727

0.081

 White

239 (50%)

170 (57%)

69 (42%)

133 (49%)

  

 Black/African American

153 (32%)

80 (27%)

73 (44%)

90 (33%)

  

 Multiracial/other

73 (15%)

49 (16%)

24 (14%)

48 (18%)

  

Ethnicity: Hispanic

65 (13%)

43 (14%)

22 (14%)

72 (26%)

<0.001

0.002

Married/committed

40 (8%)

29 (10%)

11 (7%)

35 (13%)

0.077

0.053

Medicare

238 (49%)

164 (55%)

74 (45%)

100 (38%)

<0.001

0.130

Medicaid

352 (73%)

236 (79%)

116 (70%)

169 (63%)

<0.001

0.119

Private residence

326 (68%)

213 (70%)

113 (67%)

212 (78%)

0.002

0.015

Lung condition

48 (10%)

28 (9%)

20 (12%)

15 (5%)

0.029

0.018

Smoking

346 (72%)

226 (74%)

120 (70%)

179 (64%)

0.015

0.183

Alcohol abuse

106 (22%)

73 (24%)

33 (19%)

47 (17%)

0.075

0.526

Substance abuse

114 (24%)

80 (26%)

34 (20%)

75 (27%)

0.386

0.113

Duration of schizophrenia in years (mean ± SD)

15.7 ± 12.9

16.5 ± 13.0

14.4 ± 12.5

13.9 ± 13.5

0.014

0.340

Paranoid schizophrenia

323 (67%)

203 (66%)

120 (69%)

178 (63%)

0.306

0.226

Schizophrenia severity

    

<0.001

<0.001

 Chronic

169 (35%)

108 (36%)

61 (36%)

72 (26%)

  

 Subchronic

118 (24%)

68 (23%)

50 (30%)

61 (22%)

  

 Other/unspecified

180 (38%)

123 (41%)

57 (34%)

148 (53%)

  
  1. Notes: (1) Percentage missing: age, 2%; gender, 2%; race, 4%; Hispanic ethnicity, 3%; marital status, 2%; Medicare, 4%; Medicaid, 4%; living situation, 2%; lung condition,<1%; smoking, <1%; alcohol, 1%; substance abuse, <1%; schizophrenia duration, 4%; schizophrenia severity, 2%
  2. (2) Percentages reported are among the nonmissing
  3. Abbreviations: OAT oral antipsychotic therapy, PP paliperidone palmitate, PP-C continuous user of paliperidone palmitate, PP-N new user of paliperidone palmitate, OAT oral antipsychotic therapy, SD standard deviation