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Table 2 Comparisons between depressed and non-depressed T2D patients and factors associated with depression (self-reported)

From: Depression differed by midnight cortisol secretion, alexithymia and anxiety between diabetes types: a cross sectional comparison

  

Type 2 diabetes

     

Depression (HADS-D ≥ 8 points)

 

Depression

(HADS-D ≥ 8 p)

No depression

(HADS-D < 8 p)

P-valuea

COR (95% CI)

P-value

AORb (95% CI)

P-valuec

Age (years)

51 (38, 58)

48 (41, 56)

0.77d

1.0 (0.9–1.1)

0.80

–

–

Diabetes duration (years)

14 (10, 20)

10 (6, 13)

0.066d

1.11 (0.96–1.30)

0.16

–

–

Gender

Men

2 (33)

10 (56)

0.64

2.5 (0.4–17.3)

0.35

–

–

Women

4 (67)

8 (44)

Alexithymia (TAS-20 ≥ 61 p)

4 (67)

2 (11)

0.018

16.0 (1.7–151)

0.016

15.0 (1.6–142)

0.018

Anxiety (HADS-A ≥ 8 p)

4 (67)

5 (28)

0.15

5.2 (0.7–37.9)

0.10

Irrelevant

>0.99

Physical inactivity

1 (20)

3 (19)

>0.99

1.1 (0.09–13.5)

0.95

–

–

Smoking

1 (20)

1 (6)

0.41

4.0 (0.2–78.8)

0.36

–

–

High MSC (≥ 9.3 nmol/L)

1 (17)

8 (44)

0.35

0.25 (0.02–2.59)

0.25

–

–

HbA1c (>70 mmol/mol (> 8.6%))

4 (67)

4 (22)

0.13

7.0 (0.9–53.2)

0.06

5.8 (0.4–83.5)

0.20

Obesity (BMI ≥30 kg/m2)

5 (83)

9 (50)

0.34

5.0 (0.5–51.8)

0.18

–

–

Antidepressants

1 (17)

1 (6)

0.45

3.4 (0.2–64.7)

0.42

–

–

Clinical psychiatric diagnoses

2 (40)

2 (11)

0.19

5.3 (0.5–54.0)

0.16

–

–

Foot complications

3 (50)

2 (12)

0.089

7.5 (0.9–66.1)

0.07

9.9 (0.6–157)

0.10

Cardiovascular complications

2 (33)

2 (11)

0.25

4.0 (0.4–38.0)

0.23

–

–

Diabetes retinopathy

4 (67)

10 (56)

>0.99

1.6 (0.2–11.1)

0.63

–

–

  1. aFisher’s exact test unless otherwise specified
  2. bAdjusted odds ratio
  3. cMultiple regression analysis (Backward: Wald): T2D: n = 23; Hosmer and Lemeshow test 0.875; Nagelkerke R2 Square 0.358
  4. dMann-Whitney U test