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Table 2 One-year follow-up of family-based treatment of 201 adolescents with restrictive eating disorders with features of anorexia nervosa but not fulfilling the weight criterion

From: Family-based intervention in adolescent restrictive eating disorders: early treatment response and low weight suppression is associated with favourable one-year outcome

 

EDE-Q global score at 1-year follow-up

Eating disorder at 1-year follow-up

<2.0

≥2.0

No eating disorder

Persisting eating disorder

n

130

71

106

95

Premorbid

 Age at top weight (years)

14.1 ± 1.7

14.2 ± 1.8

14.2 ± 1.6

14.0 ± 1.8

 BMISDS at top weight

0.55 ± 1.03

1.03 ± 0.88**

0.63 ± 0.93

0.76 ± 1.08

Presentation

 Gender (n; M/F)

12/118

1/71*

11/96

2/93*

 Age (years)

14.9 ± 1.6

15.2 ± 1.8

15.0 ± 1.6

15.0 ± 1.8

 Duration of ED symptoms (months)

9.5 ± 8.4

9.9 ± 9.3

10.6 ± 9.2

8.5 ± 8.0

 BMISDS

−0.69 ± 1.10

−0.32 ± 0.88*

−0.56 ± 1.08

−0.57 ± 0.99

 Weight loss (kg)

5.9 ± 5.2

7.2 ± 6.3

5.8 ± 5.4

6.9 ± 5.9

 Weight suppression (SDS)

1.25 ± 0.86

1.33 ± 0.87

1.20 ± 0.90

1.37 ± 0.81

 Exercise for weight control (n)

91 (70%)

48 (68%)

72 (68%)

67 (71%)

 Vomiting for weight control (n)

23 (18%)

16 (23%)

21 (20%)

18 (19%)

 Self-destructive behaviour (n)

15 (12%)

8 (11%)

11 (10%)

12 (13%)

 EDE-Q global score

2.6 ± 1.7

3.6 ± 1.6***

2.6 ± 1.6

3.2 ± 1.7*

 MADRS-S

16 ± 10

22 ± 11***

16 ± 10

20 ± 11*

 Depression (n)

23 (18%)

20 (28%)

18 (17%)

25 (26%)

 Neuropsychiatric diagnoses (n)

6 (5%)

3 (4%)

6 (5%)

3 (3%)

Start of treatment

 Parents accomplishing interventions during 1st week (n)

95/127 (75%)

41/65 (63%)

74/103 (72%)

62/89 (70%)

 1-week weight gain (kg)

0.6 ± 1.0

0.3 ± 0.8*

0.7 ± 1.1

0.4 ± 0.7*

 1-month weight gain (kg)

1.8 ± 1.8

0.6 ± 1.7***

1.9 ± 1.8

0.8 ± 1.6***

 3-months weight gain (kg)

4.0 ± 3.0

1.6 ± 3.2***

4.2 ± 3.1

2.0 ± 3.2***

1-year follow-up

 Age (years)

15.9 ± 1.6

16.3 ± 1.8

16.0 ± 1.6

16.1 ± 1.8

 BMISDS

0.06 ± 0.90

0.01 ± 0.96

0.17 ± 0.85

−0.11 ± 0.97*

 Weight gain (kg)

6.9 ± 4.6

3.9 ± 6.7***

7.1 ± 4.4

4.5 ± 6.4**

 Weight suppression (SDS)

0.50 ± 0.83

0.95 ± 0.95**

0.46 ± 0.74

0.88 ± 1.01***

 EDE-Q global score

0.7 ± 0.6

3.5 ± 1.0***

0.7 ± 0.7

2.8 ± 1.5***

 ED diagnoses (no ED/AN/BN/OSFEDr)

102/1/1/26 (78/1/1/20%)

4/3/2/62 (6/4/3/87%)***

125/0/0/0 (100/0/0/0%)

0/4/3/88 (0/4/3/93%)***

 MADRS-S

7 ± 7

21 ± 10***

7 ± 8

17 ± 11***

 Depression (n)

8 (6%)

24 (34%)***

7 (7%)

25 (27%)***

 Neuropsychiatric diagnoses (n)

13 (10%)

17 (24%)*

12 (11%)

19 (20%)*

  1. Values are means ± standard deviations. Significance of difference between recovered adolescents (EDE-Q < 2.0 or absence of an ED) and those with a persisting disease: *p < 0.05, **p < 0.01, ***p < 0.001 by Student’s t-test for continuous data and Chi-square test for categorical data
  2. ED eating disorder, BMI body mass index, SDS standard deviation score, EDE-Q eating disorders examination-questionnaire, MADRS-S Montgomery-Ã…sberg depression rating scale-self report, AN anorexia nervosa, BN (subthreshold) bulimia nervosa, OSFEDr other specified feeding and eating disorders-restrictive subtype