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Table 4 Summary of CANMAT guidelines for the management of ADHD and MDD [16]

From: Adult ADHD and comorbid disorders: clinical implications of a dimensional approach

Line of therapy

Recommended treatment(s)

First-line

Bupropion

Antidepressant + long-acting stimulant

Second-line

Desipramine

Nortriptyline

Venlafaxine

Third-line

Antidepressant + short-acting stimulant

Antidepressant + atomoxetine

Antidepressant + lisdexamfetamine